Richard Honkanen

Affiliations: 
University of South Alabama, Mobile, AL, United States 
Area:
Biochemistry
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"Richard Honkanen"
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Shuhaibar LC, Kaci N, Egbert JR, et al. (2021) Phosphatase inhibition by LB-100 enhances BMN-111 stimulation of bone growth. Jci Insight. 6
Papke CM, Smolen KA, Swingle MR, et al. (2021) A disorder-related variant (E420K) of a PP2A-regulatory subunit (PPP2R5D) causes constitutively active AKT-mTOR signaling and uncoordinated cell growth. The Journal of Biological Chemistry. 100313
Haldar B, Hamilton CL, Solodushko V, et al. (2020) S100A6 is a positive regulator of PPP5C-FKBP51-dependent regulation of endothelial calcium signaling. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology
D'Arcy BM, Prakash A, Honkanen RE. (2019) Targeting phosphatases in cancer: suppression of many versus the ablation of one. Oncotarget. 10: 6543-6545
D'Arcy BM, Swingle MR, Schambeau L, et al. (2019) Development of a Synthetic 3-ketosteroid Δ-dehydrogenase for the Generation of a Novel Catabolic Pathway Enabling Cholesterol Degradation in Human Cells. Scientific Reports. 9: 5969
D'Arcy BM, Swingle MR, Papke CM, et al. (2019) The Antitumor Drug LB-100 is a Catalytic Inhibitor of Protein Phosphatase 2A (PPP2CA) and 5 (PPP5C) Coordinating with the Catalytic Metals in the Active Site of PP5C. Molecular Cancer Therapeutics
Swingle MR, Honkanen RE. (2018) Inhibitors of Serine/Threonine Protein Phosphatases: Biochemical and Structural Studies Provide Insight for Further Development. Current Medicinal Chemistry
Hamilton CL, Abney KA, Vasauskas AA, et al. (2017) EXPRESS: Serine/threonine phosphatase 5 (PP5C/PPP5C) regulates the ISOC channel through a PP5C-FKBP51 axis. Pulmonary Circulation. 2045893217753156
Choy MS, Swingle M, D'Arcy B, et al. (2017) The PP1:tautomycetin complex reveals a path towards the development of PP1-specific inhibitors. Journal of the American Chemical Society
Swingle M, Volmar CH, Saldanha SA, et al. (2016) An Ultra-High-Throughput Screen for Catalytic Inhibitors of Serine/Threonine Protein Phosphatases Types 1 and 5 (PP1C and PP5C). Journal of Biomolecular Screening
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