Alan V. Smrcka
Affiliations: | University of Rochester, Rochester, NY |
Area:
Pharmacology, BiochemistryGoogle:
"Alan Victor Smrcka"Bio:
https://books.google.com/books?id=-YQvAQAAIAAJ
Mean distance: (not calculated yet)
Parents
Sign in to add mentorRichard G. Jensen | grad student | 1984-1990 | University of Arizona | |
(Structural and evolutionary factors affecting the tight binding of inhibitors by ribulose 1,5-bisphosphate carboxylase/oxygenase.) | ||||
Paul C. Sternweis | post-doc | 1990-1994 | UT Southwestern |
Children
Sign in to add traineeNaincy R Chandan | grad student | 2016- | University of Michigan |
Wenhui Wei | grad student | 2017- | Rochester |
Daniel M. Yoshikawa | grad student | 2001 | Rochester |
Junhao Mao | grad student | 2002 | Rochester |
Tabetha M. Bonacci | grad student | 2006 | Rochester |
Huan Wang | grad student | 2000-2006 | Rochester |
Chujun Yuan | grad student | 2002-2007 | Rochester |
Emily A. Oestreich | grad student | 2008 | Rochester |
Axel L. Dessal | grad student | 2010 | Rochester |
Aththanyake M. Seneviratne | grad student | 2010 | Rochester |
Lianghui Zhang | grad student | 2013 | Rochester |
Wei Kan | grad student | 2014 | Rochester |
Chinmay Surve | grad student | 2011-2015 | Rochester |
Jesi Lee Anne | grad student | 2013-2018 | Rochester |
Rafael Gil de Rubio | grad student | 2013-2018 | Rochester |
Jerry Madukwe | grad student | 2015-2018 | Rochester |
Isaac Fisher | grad student | 2014-2019 | Rochester |
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Publications
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Knight KM, Krumm BE, Kapolka NJ, et al. (2024) A neurodevelopmental disorder mutation locks G proteins in the transitory pre-activated state. Nature Communications. 15: 6643 |
Wei W, Smrcka AV. (2024) Internalized β2-Adrenergic Receptors Oppose PLC-Dependent Hypertrophic Signaling. Circulation Research |
Lefevre TJ, Wei W, Mukhaleva E, et al. (2024) Stabilization of Interdomain Interactions in G protein α Subunits as a Determinant of Gα Subtype Signaling Specificity. The Journal of Biological Chemistry. 107211 |
Wei W, Smrcka AV. (2023) Internalized β2-Adrenergic Receptors Inhibit Subcellular Phospholipase C-Dependent Cardiac Hypertrophic Signaling. Biorxiv : the Preprint Server For Biology |
Lefevre TJ, Wei W, Mukhaleva E, et al. (2023) Stabilization of Interdomain Interactions in G protein α Subunits Determines Gα Subtype Signaling Specificity. Biorxiv : the Preprint Server For Biology |
Wei W, Smrcka AV. (2022) Subcellular β-Adrenergic Receptor Signaling in Cardiac Physiology and Disease. Journal of Cardiovascular Pharmacology |
Phan HTN, Loomis J, Abraham S, et al. (2022) A Naturally Occurring Membrane-Anchored Gα Variant, XLαs, Activates Phospholipase Cβ4. The Journal of Biological Chemistry. 102134 |
Chandan NR, Abraham S, SenGupta S, et al. (2022) A network of Gα signaling partners is revealed by proximity labeling proteomics analysis and includes PDZ-RhoGEF. Science Signaling. 15: eabi9869 |
Phan HTN, Kim NH, Wei W, et al. (2021) Uveal melanoma-associated mutations in PLCβ4 are constitutively activating and promote melanocyte proliferation and tumorigenesis. Science Signaling. 14: eabj4243 |
Knight KM, Ghosh S, Campbell SL, et al. (2021) A universal allosteric mechanism for G protein activation. Molecular Cell |