James T. Stivers
Affiliations: | Johns Hopkins University, Baltimore, MD |
Area:
BiochemistryGoogle:
"James Stivers"Mean distance: (not calculated yet)
Children
Sign in to add trainee| Daniel J. Krosky | grad student | 2006 | Johns Hopkins |
| Lauren A. Seiple | grad student | 2008 | Johns Hopkins |
| Rishi H. Porecha | grad student | 2009 | Johns Hopkins |
| Amy F. Weil | grad student | 2013 | Johns Hopkins |
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Publications
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| Egleston M, Bhat S, Howlader AH, et al. (2025) Inhibitors of SAMHD1 Obtained from Chemical Tethering to the Guanine Antiviral Acyclovir. Biochemistry |
| Orris B, Sung MW, Bhat S, et al. (2023) Guanine-containing ssDNA and RNA induce dimeric and tetrameric structural forms of SAMHD1. Nucleic Acids Research |
| Orris B, Sung MW, Bhat S, et al. (2023) Guanine-containing ssDNA and RNA induce dimeric and tetrameric SAMHD1 in cryo-EM and binding studies. Biorxiv : the Preprint Server For Biology |
| Egleston M, Dong L, Howlader AH, et al. (2023) Deoxyguanosine-Linked Bifunctional Inhibitor of SAMHD1 dNTPase Activity and Nucleic Acid Binding. Acs Chemical Biology |
| Orris B, Huynh KW, Ammirati M, et al. (2022) Phosphorylation of SAMHD1 Thr592 increases C-terminal domain dynamics, tetramer dissociationĀ and ssDNA binding kinetics. Nucleic Acids Research |
| Christenson ES, Gizzi A, Cui J, et al. (2021) . Molecular Pharmacology |
| Meshesha M, Esadze A, Cui J, et al. (2020) Deficient uracil base excision repair leads to persistent dUMP in HIV proviruses during infection of monocytes and macrophages. Plos One. 15: e0235012 |
| Rodriguez G, Orris B, Majumdar A, et al. (2019) Macromolecular crowding induces compaction and DNA binding in the disordered N-terminal domain of hUNG2. Dna Repair. 86: 102764 |
| Cui J, Gizzi A, Stivers JT. (2019) Deoxyuridine in DNA has an inhibitory and promutagenic effect on RNA transcription by diverse RNA polymerases. Nucleic Acids Research |
| Esadze A, Stivers JT. (2018) Facilitated Diffusion Mechanisms in DNA Base Excision Repair and Transcriptional Activation. Chemical Reviews |