Peter R. Arvan

Affiliations: 
1988- Harvard Medical School, Boston, MA, United States 
 1996-2003 Yeshiva University, New York, NY, United States 
 2003-1988 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Cell Biology, Molecular Biology, Biochemistry
Website:
https://www.uofmhealth.org/profile/872/peter-r-arvan-md-phd
Google:
"Peter Raymond Arvan"
Bio:

https://www.brehmcoalition.org/content/peter-arvan-md-phd
https://oh.sciencehistory.org/oral-histories/arvan-peter-r
Arvan, Peter Raymond, Chemiosmotic Properties of Isolated Secretory Granules from Parotid Glands of Normal and Isoproterenol Treated Rats (1984). Yale Medicine Thesis Digital Library. 2248.
https://elischolar.library.yale.edu/ymtdl/2248

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Parents

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Efraim Racker research assistant 1977 Cornell
J. David Castle grad student 1984 Yale
 (Chemiosmotic Properties of Isolated Secretory Granules from Parotid Glands of Normal and Isoproterenol Treated Rats.)
Howard Rasmussen post-doc 1988 Yale School of Medicine (Physiology Academic Tree)
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Publications

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Tran DT, Pottekat A, Mir SA, et al. (2020) Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role For Peroxiredoxin 4 in Proinsulin Folding. Diabetes
Carrat GR, Haythorne E, Tomas A, et al. (2020) The type 2 diabetes gene product STARD10 is a phosphoinositide binding protein that controls insulin secretory granule biogenesis. Molecular Metabolism. 101015
Shrestha N, Liu T, Ji Y, et al. (2020) Sel1L-Hrd1 ER-associated degradation maintains β-cell identity via TGFβ signaling. The Journal of Clinical Investigation
Sun J, Xiong Y, Li X, et al. (2020) Role of Proinsulin Self-Association in Mutant gene-induced Diabetes of Youth. Diabetes
Rege NK, Liu M, Dhayalan B, et al. (2020) "Register-shift" insulin analogs uncover constraints of proteotoxicity in protein evolution. The Journal of Biological Chemistry
Li X, Itani OA, Haataja L, et al. (2019) Requirement for translocon-associated protein (TRAP) α in insulin biogenesis. Science Advances. 5: eaax0292
Sims EK, Syed F, Nyalwidhe J, et al. (2019) Abnormalities in proinsulin processing in islets from individuals with longstanding T1D. Translational Research : the Journal of Laboratory and Clinical Medicine
Jang I, Pottekat A, Poothong J, et al. (2019) PDIA1/P4HB is required for efficient proinsulin maturation and ß cell health in response to diet induced obesity. Elife. 8
Arunagiri A, Haataja L, Pottekat A, et al. (2019) Proinsulin misfolding is an early event in the progression to type 2 diabetes. Elife. 8
Sims EK, Bahnson HT, Nyalwidhe J, et al. (2019) Response to Comment on Sims et al. Proinsulin Secretion Is a Persistent Feature of Type 1 Diabetes. Diabetes Care 2019;42:258-264. Diabetes Care. 42: e85-e86
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