Shen-En Chen, Ph.D.
Affiliations: | 2008 | Chemistry and Biochemistry | Baylor University, Waco, TX |
Area:
Biochemistry, Physical ChemistryGoogle:
"Shen-En Chen"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Mary L. Trawick | grad student | 2008 | Baylor University | |
| (Modeling, design, and development of potential inhibitors of gamma-glutamylamine cyclotransferase and inhibitors of cruzain as therapeutic agents for Chagas' disease.) | ||||
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| Thanigaimalai P, Konno S, Yamamoto T, et al. (2013) Development of potent dipeptide-type SARS-CoV 3CL protease inhibitors with novel P3 scaffolds: design, synthesis, biological evaluation, and docking studies. European Journal of Medicinal Chemistry. 68: 372-84 |
| Thanigaimalai P, Konno S, Yamamoto T, et al. (2013) Design, synthesis, and biological evaluation of novel dipeptide-type SARS-CoV 3CL protease inhibitors: structure-activity relationship study. European Journal of Medicinal Chemistry. 65: 436-47 |
| Konno S, Thanigaimalai P, Yamamoto T, et al. (2013) Design and synthesis of new tripeptide-type SARS-CoV 3CL protease inhibitors containing an electrophilic arylketone moiety. Bioorganic & Medicinal Chemistry. 21: 412-24 |
| Song J, Jones LM, Kumar GD, et al. (2012) Synthesis and biochemical evaluation of thiochromanone thiosemicarbazone analogues as inhibitors of cathepsin L. Acs Medicinal Chemistry Letters. 3: 450-3 |
| Chavarria GE, Horsman MR, Arispe WM, et al. (2012) Initial evaluation of the antitumour activity of KGP94, a functionalized benzophenone thiosemicarbazone inhibitor of cathepsin L. European Journal of Medicinal Chemistry. 58: 568-72 |
| Kishore Kumar GD, Chavarria GE, Charlton-Sevcik AK, et al. (2010) Design, synthesis, and biological evaluation of potent thiosemicarbazone based cathepsin L inhibitors. Bioorganic & Medicinal Chemistry Letters. 20: 1415-9 |
| Trawick ML, Arispe‐Angulo WM, Chen S, et al. (2007) Kinetics of Thiosemicarbazone‐Based Inhibitors of Cathepsin L The Faseb Journal. 21 |
| Chen S, Siles RE, Zhou M, et al. (2007) Kinetic Studies of Potent Thiosemicarbazone Inhibitors of Cruzain The Faseb Journal. 21 |
| Siles R, Chen SE, Zhou M, et al. (2006) Design, synthesis, and biochemical evaluation of novel cruzain inhibitors with potential application in the treatment of Chagas' disease. Bioorganic & Medicinal Chemistry Letters. 16: 4405-9 |