Gustavo E. Chavarria, Ph.D.
|2012||Chemistry and Biochemistry||Baylor University, Waco, TX|
Area:Biochemistry, Cell Biology
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|Parker EN, Song J, Kishore Kumar GD, et al. (2015) Synthesis and biochemical evaluation of benzoylbenzophenone thiosemicarbazone analogues as potent and selective inhibitors of cathepsin L. Bioorganic & Medicinal Chemistry|
|Song J, Jones LM, Chavarria GE, et al. (2013) Small-molecule inhibitors of cathepsin L incorporating functionalized ring-fused molecular frameworks. Bioorganic & Medicinal Chemistry Letters. 23: 2801-7|
|Song J, Jones LM, Kumar GD, et al. (2012) Synthesis and biochemical evaluation of thiochromanone thiosemicarbazone analogues as inhibitors of cathepsin L. Acs Medicinal Chemistry Letters. 3: 450-3|
|Chavarria GE, Horsman MR, Arispe WM, et al. (2012) Initial evaluation of the antitumour activity of KGP94, a functionalized benzophenone thiosemicarbazone inhibitor of cathepsin L. European Journal of Medicinal Chemistry. 58: 568-72|
|Trawick ML, Pinney KG, Chaplin DJ, et al. (2011) Abstract 1416: Development and initial evaluation of the antitumor activity of a functionalized benzophenone thiosemicarbazone inhibitor of cathepsin L Cancer Research. 71: 1416-1416|
|Kumar GD, Chavarria GE, Charlton-Sevcik AK, et al. (2010) Functionalized benzophenone, thiophene, pyridine, and fluorene thiosemicarbazone derivatives as inhibitors of cathepsin L. Bioorganic & Medicinal Chemistry Letters. 20: 6610-5|
|Kishore Kumar GD, Chavarria GE, Charlton-Sevcik AK, et al. (2010) Design, synthesis, and biological evaluation of potent thiosemicarbazone based cathepsin L inhibitors. Bioorganic & Medicinal Chemistry Letters. 20: 1415-9|