Michael C. Mossing

Affiliations: 
The University of Mississippi, USA 
Area:
Biochemistry
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"Michael Mossing"
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Parents

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M Thomas Record grad student 1985 UW Madison
 (ORIGINS OF PROTEIN-DNA BINDING SPECIFICITY: OBSERVATIONS ON THE LAC REPRESSOR-OPERATOR INTERACTION (THERMODYNAMICS, COOPERATIVITY))
Robert T. Sauer post-doc 1986-1990 MIT
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Publications

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Harris JJ, Duarte CW, Mossing MC. (2011) Using protein abundance to indicate underlying mRNA expression levels in E.coli: an SEM modelling approach. International Journal of Computational Biology and Drug Design. 4: 387-95
Jia H, Satumba WJ, Bidwell GL, et al. (2005) Slow assembly and disassembly of lambda Cro repressor dimers. Journal of Molecular Biology. 350: 919-29
Maity H, Mossing MC, Eftink MR. (2005) Equilibrium unfolding of dimeric and engineered monomeric forms of lambda Cro (F58W) repressor and the effect of added salts: evidence for the formation of folded monomer induced by sodium perchlorate. Archives of Biochemistry and Biophysics. 434: 93-107
Mollah AK, Stennis RL, Mossing MC. (2003) Stability of monomeric Cro variants: Isoenergetic transformation of a type I' to a type II' beta-hairpin by single amino acid replacements. Protein Science : a Publication of the Protein Society. 12: 1126-30
Satumba WJ, Mossing MC. (2002) Folding and assembly of lambda Cro repressor dimers are kinetically limited by proline isomerization. Biochemistry. 41: 14216-24
Nilsson MT, Mossing MC, Widersten M. (2000) Functional expression and affinity selection of single-chain cro by phage display: isolation of novel DNA-binding proteins. Protein Engineering. 13: 519-26
Rupert PB, Mollah AK, Mossing MC, et al. (2000) The structural basis for enhanced stability and reduced DNA binding seen in engineered second-generation Cro monomers and dimers. Journal of Molecular Biology. 296: 1079-90
Albright RA, Mossing MC, Matthews BW. (1998) Crystal structure of an engineered Cro monomer bound nonspecifically to DNA: possible implications for nonspecific binding by the wild-type protein. Protein Science : a Publication of the Protein Society. 7: 1485-94
Jana R, Hazbun TR, Fields JD, et al. (1998) Single-chain lambda Cro repressors confirm high intrinsic dimer-DNA affinity. Biochemistry. 37: 6446-55
Mossing MC. (1998) Solution structure and dynamics of a designed monomeric variant of the lambda Cro repressor. Protein Science : a Publication of the Protein Society. 7: 983-93
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