Manju M. Hingorani
Affiliations: | Wesleyan University, Middletown, CT, United States |
Area:
General Biophysics, BiochemistryGoogle:
"Manju Hingorani"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Smita S. Patel | grad student | 1996 | Ohio State | |
| (Role of Hexameric Structure and dTTPase Activity in Bacteriophage T7 Helicase-Catalyzed Unwinding of Double-Stranded DNA.) | ||||
| Michael E. O'Donnell | post-doc | Rockefeller | ||
Children
Sign in to add trainee| Edwin Antony | grad student | 2005 | Wesleyan |
| Maria-Magdalena Coman | grad student | 2007 | Wesleyan |
| Siying Chen | grad student | 2008 | Wesleyan |
| Jie Zhai | grad student | 2011 | Wesleyan |
| Yayan Zhou | grad student | 2012 | Wesleyan |
| Anushi Sharma | grad student | 2014 | Wesleyan |
| Bo Song | grad student | 2018 | Wesleyan |
| Brandon Case | grad student | 2019 | Wesleyan |
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Publications
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| Jayaraj A, Thayer KM, Beveridge DL, et al. (2023) Molecular Dynamics of Mismatch Detection - How MutS Uses Indirect Readout to Find Errors in DNA. Biophysical Journal |
| Hao P, LeBlanc SJ, Case BC, et al. (2020) Recurrent mismatch binding by MutS mobile clamps on DNA localizes repair complexes nearby. Proceedings of the National Academy of Sciences of the United States of America |
| Lombardo Z, Lahiri S, Lakhani B, et al. (2020) Investigating the Role of Msh4-Msh5 ATPASE Activity During Homologous Recombination Biophysical Journal. 118: 73a |
| Li Y, Lombardo Z, Joshi M, et al. (2019) Mismatch Recognition by Msh2-Msh6: Role of Structure and Dynamics. International Journal of Molecular Sciences. 20 |
| Case BC, Hartley S, Osuga M, et al. (2019) The ATPase mechanism of UvrA2 reveals the distinct roles of proximal and distal ATPase sites in nucleotide excision repair. Nucleic Acids Research |
| Qiu R, DeRocco VC, Harris C, et al. (2019) Large conformational changes in MutS during DNA scanning, mismatch recognition and repair signaling. The Embo Journal. 38 |
| Lahiri S, Li Y, Hingorani MM, et al. (2018) MutSγ-Induced DNA Conformational Changes Provide Insights into its Role in Meiotic Recombination. Biophysical Journal |
| LeBlanc SJ, Gauer JW, Hao P, et al. (2018) Coordinated protein and DNA conformational changes govern mismatch repair initiation by MutS. Nucleic Acids Research |
| Song B, Hamdan SM, Hingorani MM. (2018) Positioning the 5'-flap junction in the active site controls the rate of flap endonuclease-1-catalyzed DNA cleavage. The Journal of Biological Chemistry |
| Zaher MS, Rashid F, Song B, et al. (2018) Missed cleavage opportunities by FEN1 lead to Okazaki fragment maturation via the long-flap pathway. Nucleic Acids Research |