Irene Lee

Affiliations: 
Case Western Reserve University, Cleveland Heights, OH, United States 
Area:
Biochemistry
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"Irene Lee"
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Publications

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Sha Z, Fishovitz J, Wang S, et al. (2020) A Selective Fluorogenic Peptide Substrate for the Human Mitochondrial ATP-Dependent Protease Complex ClpXP. Chembiochem : a European Journal of Chemical Biology
Sha Z, Chilakala S, Crabill G, et al. (2020) A Proteolytic Site-Directed Affinity Label to Inhibit the Human ATP-Dependent Protease Caseinolytic Complex XP. Chembiochem : a European Journal of Chemical Biology
Fishovitz J, Sha Z, Chilakala S, et al. (2017) Utilization of Mechanistic Enzymology to Evaluate the Significance of ADP Binding to Human Lon Protease. Frontiers in Molecular Biosciences. 4: 47
Lee I, Berdis AJ. (2016) Physiological enzymology: The next frontier in understanding protein structure and function at the cellular level. Biochimica Et Biophysica Acta. 1864: 65-9
Golden J, Motea E, Zhang X, et al. (2013) Development and characterization of a non-natural nucleoside that displays anticancer activity against solid tumors. Acs Chemical Biology. 8: 2452-65
Mikita N, Cheng I, Fishovitz J, et al. (2013) Processive degradation of unstructured protein by Escherichia coli Lon occurs via the slow, sequential delivery of multiple scissile sites followed by rapid and synchronized peptide bond cleavage events. Biochemistry. 52: 5629-44
Motea EA, Lee I, Berdis AJ. (2013) Insights into the roles of desolvation and π-electron interactions during DNA polymerization. Chembiochem : a European Journal of Chemical Biology. 14: 489-98
Devadoss B, Lee I, Berdis AJ. (2013) Spectroscopic analysis of polymerization and exonuclease proofreading by a high-fidelity DNA polymerase during translesion DNA synthesis. Biochimica Et Biophysica Acta. 1834: 34-45
Motea EA, Lee I, Berdis AJ. (2012) A non-natural nucleoside with combined therapeutic and diagnostic activities against leukemia. Acs Chemical Biology. 7: 988-98
Cheng I, Mikita N, Fishovitz J, et al. (2012) Identification of a region in the N-terminus of Escherichia coli Lon that affects ATPase, substrate translocation and proteolytic activity. Journal of Molecular Biology. 418: 208-25
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