Ramachandra S. Hosmane

Affiliations: 
Chemistry University of Maryland, Baltimore County, Baltimore, MD, United States 
Area:
Organic Chemistry, Virology Biology
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Wang L, Hosmane RS. (2010) ChemInform Abstract: A Unique Ring-Expanded Acyclic Nucleoside Analogue that Inhibits both Adenosine Deaminase (ADA) and Guanine Deaminase (GDA; Guanase): Synthesis and Enzyme Inhibition Studies of 4,6-Diamino-8H-1-hydroxyethoxymethyl-8-iminoimidazo[4,5-e Cheminform. 33: no-no
Ujjinamatada RK, Paulman RL, Ptak RG, et al. (2006) Nucleosides with self-complementary hydrogen-bonding motifs: synthesis and base-pairing studies of two nucleosides containing the imidazo[4,5-d]pyridazine ring system. Bioorganic & Medicinal Chemistry. 14: 6359-67
Sood R, Bhadti V, Chen H, et al. (2001) 6-Amino-1-(2’-deoxy-b-D-ribofuranosyl)-4,5-dihydro-8H-imidazo[4,5-e][1,3]diazepine-4,8-dione Molecules. 6: M264
Chen H, Hosmane R. (2001) Synthesis of 1-(2'-O-Methyl-ß-D-ribofuranosyl)-1H-imidazo[4,5-d]pyridazine-4,7(5H,6H)-dione: An Attractive Building Block for Antisense and Triple-helical Applications Molecules. 6: 203-207
Chen H, Hosmane R. (2000) 6-Amino-2-phenylimidazo[4,5-e][1,3]diazepine-4,8(1H, 5H)-dione Molecules. 5: M164
Chen H, Hosmane R. (2000) Synthesis of 1-(2'-Deoxy-ß-D-ribofuranosyl)-1H-imidazo[4,5-d]-pyridazine-4,7(5H,6H)-dione: A Potential Building Block for Antisense Applications Molecules. 5: 1187-1193
Rajappan VP, Hosmane RS. (1998) Analogues of azepinomycin as inhibitors of guanase. Nucleosides & Nucleotides. 17: 1141-51
Bhan A, Hosmane RS, Zhang H, et al. (1994) Ring closure of diethyl 2-methoxy-2-[N-(5-amino-1-benzylimidazolyl-4-carbonyl)amino]malonate: Product structures and pathways of product formation Structural Chemistry. 5: 375-381
Hosmane RS, Vaidya VP, Chung MK, et al. (1991) Synthesis of Ring-Expanded Xanthines and Xanthosines Containing the Imidazo[4,5-d][1,3]diazepine Ring System Nucleosides and Nucleotides. 10: 1693-1706
Hosmane RS, Bhan A, Karpel RL, et al. (1990) The synthesis and biophysical investigations of novel ring-expanded nucleosides, nucleotides, and homopolymers containing the 5:7-fused heterocyclic ring system, imidazo[4,5-e][1,4]diazepine The Journal of Organic Chemistry. 55: 5882-5890
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