☰ Chemistry Tree

Ronald E. Viola

Affiliations:	1989-2000		University of Akron, Akron, OH, United States
	2000-		The University of Toledo

Area:

Biochemistry

Website:

http://www.utoledo.edu/nsm/chemistry/people/Webpages/Viola.html

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"Ronald Edward Viola"

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Parents

Joseph J. Villafranca	grad student	1976	Penn State
W. Wallace Cleland	post-doc	1977-1979	UW Madison

Children

Julio Blanco	grad student	2003	The University of Toledo
Shoufa Han	grad student	2003	The University of Toledo
Christopher R. Faehnle	grad student	2006	The University of Toledo
Johanne Le Coq	grad student	2006	The University of Toledo
David M. Coe	grad student	2007	The University of Toledo
Jeffrey F. Ohren	grad student	2007	The University of Toledo
Buenafe T. Arachea	grad student	2011	The University of Toledo
Stephen P. Zano	grad student	2013	The University of Toledo
Yasanandana S. Wijayasinghe	grad student	2014	The University of Toledo
Gopal P. Dahal	grad student	2013-2018	The University of Toledo

Collaborators

BETA: Related publications

Publications

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Wijayasinghe YS, Bhansali MP, Borkar MR, et al. (2022) A Comprehensive Biological and Synthetic Perspective on 2-Deoxy-d-Glucose (2-DG), A Sweet Molecule with Therapeutic and Diagnostic Potentials. Journal of Medicinal Chemistry. 65: 3706-3728
Friday SN, Cheng DW, Zagler SG, et al. (2021) Design and testing of selective inactivators against an antifungal enzyme target. Drug Development Research
Hussain MS, Wang Q, Viola RE. (2021) Engineering of a critical membrane-anchored enzyme for high solubility and catalytic activity. Archives of Biochemistry and Biophysics. 108870
Wijayasinghe YS, Bhansali P, Viola RE, et al. (2020) Natural Products: A Rich Source of Antiviral Drug Lead Candidates for the Management of COVID-19. Current Pharmaceutical Design
Stecula A, Hussain MS, Viola RE. (2020) Discovery of Novel Inhibitors of a Critical Brain Enzyme Using a Homology Model and a Deep Convolutional Neural Network. Journal of Medicinal Chemistry
Dahal GP, Launder D, McKeone KMM, et al. (2020) Aspartate semialdehyde dehydrogenase inhibition suppresses the growth of the pathogenic fungus Candida albicans. Drug Development Research
Viola RE. (2020) The ammonia-lyases: enzymes that use a wide range of approaches to catalyze the same type of reaction. Critical Reviews in Biochemistry and Molecular Biology. 1-17
Mutthamsetty V, Dahal GP, Wang Q, et al. (2019) Development of bisubstrate analog inhibitors of aspartate N-acetyltransferase, a critical brain enzyme. Chemical Biology & Drug Design
Ohren J, Parungao GG, Viola RE. (2019) Structure of a critical metabolic enzyme: S-adenosylmethionine synthetase from Cryptosporidium parvum. Acta Crystallographica. Section F, Structural Biology Communications. 75: 290-298
Dahal GP, Viola RE. (2018) Structural insights into inhibitor binding to a fungal ortholog of aspartate semialdehyde dehydrogenase. Biochemical and Biophysical Research Communications

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