George M. Carman

Affiliations: 
Rutgers University, New Brunswick, New Brunswick, NJ, United States 
Area:
Biochemistry
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"George Carman"
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Publications

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Carman GM, Stukey GJ, Jog R, et al. (2025) Insights into phosphatidic acid phosphatase and its potential role as a therapeutic target. Advances in Biological Regulation. 101074
Stukey GJ, Breuer MR, Burchat N, et al. (2024) The antidepressant drug sertraline is a novel inhibitor of yeast Pah1 and human lipin 1 phosphatidic acid phosphatases. Journal of Lipid Research. 100711
Jog R, Han GS, Carman GM. (2024) The CTR hydrophobic residues of Nem1 catalytic subunit are required to form a protein phosphatase complex with Spo7 to activate yeast Pah1 PA phosphatase. The Journal of Biological Chemistry. 300: 108003
Stukey GJ, Han GS, Carman GM. (2024) Architecture and function of yeast phosphatidate phosphatase Pah1 domains/regions. Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids. 159547
Khondker S, Han GS, Carman GM. (2024) Protein kinase Hsl1 phosphorylates Pah1 to inhibit phosphatidate phosphatase activity and regulate lipid synthesis in Saccharomyces cerevisiae. The Journal of Biological Chemistry. 300: 107572
Jog R, Han GS, Carman GM. (2023) The Saccharomyces cerevisiae Spo7 basic tail is required for Nem1-Spo7/Pah1 phosphatase cascade function in lipid synthesis. The Journal of Biological Chemistry. 105587
Han GS, Kwiatek JM, Hu KS, et al. (2023) Catalytic core function of yeast Pah1 phosphatidate phosphatase reveals structural insight into its membrane localization and activity control. The Journal of Biological Chemistry. 105560
Stukey GJ, Han GS, Carman GM. (2023) Phosphatidate phosphatase Pah1 contains a novel RP domain that regulates its phosphorylation and function in yeast lipid synthesis. The Journal of Biological Chemistry. 299: 105025
Dhakephalkar T, Stukey G, Guan Z, et al. (2023) Characterization of an evolutionarily distinct bacterial ceramide kinase from Caulobacter crescentus. The Journal of Biological Chemistry. 104894
Dhakephalkar T, Stukey G, Guan Z, et al. (2023) Characterization of an evolutionarily distinct bacterial ceramide kinase from . Biorxiv : the Preprint Server For Biology
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