Mary Kay H. Pflum

2001- Chemistry Wayne State University, Detroit, MI, United States 
Biochemistry, Cell Biology
"Mary Kay Hamm Pflum"

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Jerry R. Mohrig research assistant 1992 Carleton College
Alanna Schepartz grad student 1999 Yale
 (BZIP proteins and their accessory factors : DNA binding and transcription activation.)
Stuart L. Schreiber post-doc 2001 Harvard
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Gomes ID, Pflum MKH. (2019) Optimal Substrate-Trapping Mutants to Discover Substrates of HDAC1. Chembiochem : a European Journal of Chemical Biology. 20: 1444-1449
Nalawansha DA, Zhang Y, Herath K, et al. (2018) HDAC1 Substrate Profiling using Proteomics-Based Substrate Trapping. Acs Chemical Biology
Garre S, Gamage AK, Faner TR, et al. (2018) Identification of Kinases and Interactors of p53 Using Kinase-Catalyzed Cross-Linking and Immunoprecipitation. Journal of the American Chemical Society
Anthony TM, Pflum MKH. (2018) Kinase-catalyzed biotinylation of DNA. Bioorganic & Medicinal Chemistry
Dedigama-Arachchige PM, Acharige NPN, Pflum MKH. (2018) Identification of PP1-Gadd34 substrates involved in the unfolded protein response using K-BIPS, a method for phosphatase substrate identification. Molecular Omics. 14: 121-133
Negmeldin AT, Knoff JR, Pflum MKH. (2017) The structural requirements of histone deacetylase inhibitors: C4-modified SAHA analogs display dual HDAC6/HDAC8 selectivity. European Journal of Medicinal Chemistry
Negmeldin AT, Pflum MKH. (2017) The structural requirements of histone deacetylase inhibitors: SAHA analogs modified at the C5 position display dual HDAC6/8 selectivity. Bioorganic & Medicinal Chemistry Letters. 27: 3254-3258
Nalawansha DA, Gomes ID, Wambua MK, et al. (2017) HDAC Inhibitor-Induced Mitotic Arrest Is Mediated by Eg5/KIF11 Acetylation. Cell Chemical Biology
Negmeldin AT, Padige G, Bieliauskas AV, et al. (2017) Structural Requirements of HDAC Inhibitors: SAHA Analogues Modified at the C2 Position Display HDAC6/8 Selectivity. Acs Medicinal Chemistry Letters. 8: 281-286
Nalawansha DA, Pflum MK. (2017) LSD1 Substrate Binding and Gene Expression Are Affected by HDAC1-Mediated Deacetylation. Acs Chemical Biology. 12: 254-264
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