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Lesa J. Beamer

Affiliations: 
University of Missouri - Columbia, Columbia, MO, United States 
Area:
Biochemistry
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"Lesa Beamer"
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Catherine A. Regni grad student 2005 University of Missouri - Columbia

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Stiers KM, Owuocha LF, Beamer LJ. (2022) Effects of the T337M and G391V disease-related variants on human phosphoglucomutase 1: structural disruptions large and small. Acta Crystallographica. Section F, Structural Biology Communications. 78: 200-209
Beamer LJ. (2020) Enzyme dysfunction at atomic resolution: Disease-associated variants of human phosphoglucomutase-1. Biochimie
Korasick DA, Kandoth PK, Tanner JJ, et al. (2020) Impaired folate binding of serine hydroxymethyltransferase 8 from soybean underlies resistance to the soybean cyst nematode. The Journal of Biological Chemistry
Zhu JS, Stiers KM, Soleimani E, et al. (2019) Inhibitory Evaluation of αPMM/PGM from : Chemical Synthesis, Enzyme Kinetics, and Protein Crystallographic Study. The Journal of Organic Chemistry
Stiers KM, Graham AC, Zhu JS, et al. (2019) Structural and dynamical description of the enzymatic reaction of a phosphohexomutase. Structural Dynamics (Melville, N.Y.). 6: 024703
Stiers KM, Beamer LJ. (2018) Assessment and Impacts of Phosphorylation on Protein Flexibility of the α-d-Phosphohexomutases. Methods in Enzymology. 607: 241-267
Stiers KM, Beamer LJ. (2018) A Hotspot for Disease-Associated Variants of Human PGM1 Is Associated with Impaired Ligand Binding and Loop Dynamics. Structure (London, England : 1993)
Stiers KM, Xu J, Lee Y, et al. (2017) Phosphorylation-Dependent Effects on the Structural Flexibility of Phosphoglucosamine Mutase from . Acs Omega. 2: 8445-8452
Muenks AG, Stiers KM, Beamer LJ. (2017) Sequence-structure relationships, expression profiles, and disease-associated mutations in the paralogs of phosphoglucomutase 1. Plos One. 12: e0183563
Xu J, Sarma AVS, Wei Y, et al. (2017) Multiple Ligand-Bound States of a Phosphohexomutase Revealed by Principal Component Analysis of NMR Peak Shifts. Scientific Reports. 7: 5343
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