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Adam L. Raes

Affiliations: 
Universiteit Antwerpen (Belgium) 
Area:
Biochemistry
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"Adam Raes"
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Children

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Natacha Ottschytsch grad student 2005 Universiteit Antwerpen (Belgium)
Inge R. Boulet grad student 2007 Universiteit Antwerpen (Belgium)

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Publications

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Labro AJ, Boulet IR, Choveau FS, et al. (2011) The S4-S5 linker of KCNQ1 channels forms a structural scaffold with the S6 segment controlling gate closure. The Journal of Biological Chemistry. 286: 717-25
Labro AJ, Boulet IR, Raes AL, et al. (2010) Substitution Scan of the S4-S5 Linker Region in KCNQ1 Channel: Structural Scaffold for Critical Protein Interactions Biophysical Journal. 98: 120a-121a
Bocksteins E, Raes AL, Van de Vijver G, et al. (2009) Kv2.1 and silent Kv subunits underlie the delayed rectifier K+ current in cultured small mouse DRG neurons. American Journal of Physiology. Cell Physiology. 296: C1271-8
Labro AJ, Grottesi A, Raes AL, et al. (2009) A P-helix Mutant In A Shaker-type Kv Channel Converts The Inactivated State Into A Conducting One Biophysical Journal. 96: 656a-657a
Labro AJ, Raes AL, Grottesi A, et al. (2008) Kv channel gating requires a compatible S4-S5 linker and bottom part of S6, constrained by non-interacting residues. The Journal of General Physiology. 132: 667-80
Labro AJ, Grottesi A, Sansom MS, et al. (2008) A Kv channel with an altered activation gate sequence displays both "fast" and "slow" activation kinetics. American Journal of Physiology. Cell Physiology. 294: C1476-84
Cuypers E, Abdel-Mottaleb Y, Kopljar I, et al. (2008) Gambierol, a toxin produced by the dinoflagellate Gambierdiscus toxicus, is a potent blocker of voltage-gated potassium channels. Toxicon : Official Journal of the International Society On Toxinology. 51: 974-83
Boulet IR, Labro AJ, Raes AL, et al. (2007) Role of the S6 C-terminus in KCNQ1 channel gating. The Journal of Physiology. 585: 325-37
Van Hoorick D, Raes A, Snyders DJ. (2007) The aromatic cluster in KCHIP1b affects Kv4 inactivation gating. The Journal of Physiology. 583: 959-69
Saenen JB, Paulussen AD, Jongbloed RJ, et al. (2007) A single hERG mutation underlying a spectrum of acquired and congenital long QT syndrome phenotypes. Journal of Molecular and Cellular Cardiology. 43: 63-72
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