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Donovan C. Haines

Affiliations: 
2001-2008 University of Texas at Dallas, Richardson, TX, United States 
 2008- Sam Houston State University, Huntsville, TX, United States 
Area:
Biochemistry
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Parents

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Kandatege Wimalasena grad student 1994-1999 Wichita State University
Julian A. Peterson post-doc 1999-2001 University of Texas Southwestern Medical Center at Dallas

Children

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Gabriela Luta grad student 2003 UT Dallas
Puneet K. Chowdhary grad student 2006 UT Dallas

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Publications

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Winborn J, Haines D, Kerrigan S. (2018) In vitro metabolism of desomorphine. Forensic Science International. 289: 140-149
Davydov DR, Ponomarev GV, Bobrovnikova-Marjon E, et al. (2013) Aluminum-substituted heme domain of P450BM-3 (BMP): introducing a heme-derived fluorescent probe for studies of substrate binding and protein-protein interactions in cytochromes P450. Biotechnology and Applied Biochemistry. 60: 41-51
Marziaz ML, Frazier K, Guidry PB, et al. (2013) Comparison of brain mitochondrial cytochrome c oxidase activity with cyanide LD(50) yields insight into the efficacy of prophylactics. Journal of Applied Toxicology : Jat. 33: 50-5
De Matteis F, Ballou DP, Coon MJ, et al. (2012) Peroxidase-like activity of uncoupled cytochrome P450: studies with bilirubin and toxicological implications of uncoupling. Biochemical Pharmacology. 84: 374-82
Haines DC, Hegde A, Chen B, et al. (2011) A single active-site mutation of P450BM-3 dramatically enhances substrate binding and rate of product formation. Biochemistry. 50: 8333-41
Horke S, Witte I, Altenhöfer S, et al. (2010) Paraoxonase 2 is down-regulated by the Pseudomonas aeruginosa quorumsensing signal N-(3-oxododecanoyl)-L-homoserine lactone and attenuates oxidative stress induced by pyocyanin. The Biochemical Journal. 426: 73-83
Falck JR, Reddy YK, Haines DC, et al. (2010) ChemInform Abstract: Practical, Enantiospecific Syntheses of 14,15-EET and Leukotoxin B (Vernolic Acid). Cheminform. 33: no-no
Chowdhary PK, Stewart L, Lopez C, et al. (2008) A single mutation in P450BM-3 enhances acyl homoserine lactone: acyl homoserine substrate binding selectivity nearly 250-fold. Journal of Biotechnology. 135: 374-6
Teiber JF, Horke S, Haines DC, et al. (2008) Dominant role of paraoxonases in inactivation of the Pseudomonas aeruginosa quorum-sensing signal N-(3-oxododecanoyl)-L-homoserine lactone. Infection and Immunity. 76: 2512-9
Haines DC, Chen B, Tomchick DR, et al. (2008) Crystal structure of inhibitor-bound P450BM-3 reveals open conformation of substrate access channel. Biochemistry. 47: 3662-70
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