Constance E. Brinckerhoff

Biochemistry Dartmouth College, Hanover, NH, United States 
Molecular Biology
"Constance Brinckerhoff"
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David W. Mullins collaborator 2011- Dartmouth (Microtree)
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Bellmann L, Cappellano G, Schachtl-Riess JF, et al. (2019) A TLR7 agonist strengthens T and NK cell function during BRAF-targeted therapy in a preclinical melanoma model. International Journal of Cancer
Whipple CA, Boni A, Fisher JL, et al. (2016) The mitogen-activated protein kinase pathway plays a critical role in regulating immunological properties of BRAF mutant cutaneous melanoma cells. Melanoma Research
Jenkins MH, Croteau W, Mullins DW, et al. (2015) The BRAF(V600E) inhibitor, PLX4032, increases type I collagen synthesis in melanoma cells. Matrix Biology : Journal of the International Society For Matrix Biology. 48: 66-77
Jenkins MH, Brinckerhoff CE, Mullins DW. (2015) CXCR3 signaling in BRAFWT melanoma increases IL-8 expression and tumorigenicity. Plos One. 10: e0121140
Steinberg SM, Zhang P, Malik BT, et al. (2014) BRAF inhibition alleviates immune suppression in murine autochthonous melanoma. Cancer Immunology Research. 2: 1044-50
Whipple CA, Brinckerhoff CE. (2014) BRAF V600E melanoma cells secrete factors that activate stromal fibroblasts and enhance tumourigenicity British Journal of Cancer. 111: 1625-1633
Jenkins MH, Steinberg SM, Alexander MP, et al. (2014) Multiple murine BRaf(V600E) melanoma cell lines with sensitivity to PLX4032. Pigment Cell & Melanoma Research. 27: 495-501
Croteau W, Jenkins MH, Ye S, et al. (2013) Differential mechanisms of tumor progression in clones from a single heterogeneous human melanoma. Journal of Cellular Physiology. 228: 773-80
Schmucker AC, Wright JB, Cole MD, et al. (2012) Distal interleukin-1β (IL-1β) response element of human matrix metalloproteinase-13 (MMP-13) binds activator protein 1 (AP-1) transcription factors and regulates gene expression. The Journal of Biological Chemistry. 287: 1189-97
Eck SM, Blackburn JS, Schmucker AC, et al. (2009) Matrix metalloproteinase and G protein coupled receptors: co-conspirators in the pathogenesis of autoimmune disease and cancer. Journal of Autoimmunity. 33: 214-21
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