Richard J. Youle

Affiliations: 
Biochemistry and Molecular Genetics The George Washington University, Washington, DC, United States 
Area:
Cell Biology, Virology Biology
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"Richard Youle"
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Publications

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Lomash RM, Petralia RS, Holtzclaw LA, et al. (2019) Neurolastin, a dynamin family GTPase, translocates to mitochondria upon neuronal stress and alters mitochondrial morphology in vivo. The Journal of Biological Chemistry
Richter B, Sliter DA, Herhaus L, et al. (2016) Phosphorylation of OPTN by TBK1 enhances its binding to Ub chains and promotes selective autophagy of damaged mitochondria. Proceedings of the National Academy of Sciences of the United States of America
Sun N, Youle RJ, Finkel T. (2016) The Mitochondrial Basis of Aging. Molecular Cell. 61: 654-66
Yao Y, Nisan D, Antignani A, et al. (2016) Characterization of the membrane-inserted C-terminus of cytoprotective BCL-XL. Protein Expression and Purification. 122: 56-63
Lazarou M, Sliter DA, Kane LA, et al. (2015) The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy. Nature. 524: 309-14
Lomash RM, Gu X, Youle RJ, et al. (2015) Neurolastin, a Dynamin Family GTPase, Regulates Excitatory Synapses and Spine Density. Cell Reports
Pickrell AM, Huang CH, Kennedy SR, et al. (2015) Endogenous Parkin Preserves Dopaminergic Substantia Nigral Neurons following Mitochondrial DNA Mutagenic Stress. Neuron. 87: 371-81
Hasson SA, Fogel AI, Wang C, et al. (2015) Chemogenomic profiling of endogenous PARK2 expression using a genome-edited coincidence reporter. Acs Chemical Biology. 10: 1188-97
Kane LA, Lazarou M, Fogel AI, et al. (2014) PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity. The Journal of Cell Biology. 205: 143-53
Yamano K, Fogel AI, Wang C, et al. (2014) Mitochondrial Rab GAPs govern autophagosome biogenesis during mitophagy. Elife. 3: e01612
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