Young-Sam Keum, Ph.D.
Affiliations: | 2007 | Rutgers University, New Brunswick, New Brunswick, NJ, United States |
Area:
Pharmacology, Oncology, BiochemistryGoogle:
"Young-Sam Keum"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Ah-Ng T. Kong | grad student | 2007 | Rutgers, New Brunswick | |
| (The induction of phase II detoxifying enzymes and prostate cancer prevention by chemopreventive isothiocyanates.) | ||||
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Publications
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| Yu BY, Ngo HH, Choi WJ, et al. (2023) Dimethyl Itaconate Inhibits Melanogenesis in B16F10 Cells. Antioxidants (Basel, Switzerland). 12 |
| Kang JS, Nam LB, Yoo OK, et al. (2020) Molecular mechanisms and systemic targeting of NRF2 dysregulation in cancer. Biochemical Pharmacology. 177: 114002 |
| Lee J, Kang JS, Ba Nam L, et al. (2018) Suppression of NRF2/ARE by convallatoxin sensitizes A549 cells to 5-FU-mediated apoptosis. Free Radical Research. 1-141 |
| Jeong J, Wahyudi LD, Keum YS, et al. (2018) E-p-Methoxycinnamoyl-α-l-rhamnopyranosyl Ester, a Phenylpropanoid Isolated from Scrophularia buergeriana, Increases Nuclear Factor Erythroid-Derived 2-Related Factor 2 Stability by Inhibiting Ubiquitination in Human Keratinocytes. Molecules (Basel, Switzerland). 23 |
| Kim J, Keum YS. (2016) NRF2, a Key Regulator of Antioxidants with Two Faces towards Cancer. Oxidative Medicine and Cellular Longevity. 2016: 2746457 |
| Lee MH, Hong SH, Park C, et al. (2016) Hwang-Heuk-San induces apoptosis in HCT116 human colorectal cancer cells through the ROS-mediated activation of caspases and the inactivation of the PI3K/Akt signaling pathway. Oncology Reports |
| Kim S, Lee HG, Park SA, et al. (2014) Keap1 cysteine 288 as a potential target for diallyl trisulfide-induced Nrf2 activation. Plos One. 9: e85984 |
| Yun DK, Lee J, Keum YS. (2013) Finasteride Increases the Expression of Hemoxygenase-1 (HO-1) and NF-E2-Related Factor-2 (Nrf2) Proteins in PC-3 Cells: Implication of Finasteride-Mediated High-Grade Prostate Tumor Occurrence. Biomolecules & Therapeutics. 21: 49-53 |
| Das BN, Kim YW, Keum YS. (2013) Mechanisms of Nrf2/Keap1-dependent phase II cytoprotective and detoxifying gene expression and potential cellular targets of chemopreventive isothiocyanates. Oxidative Medicine and Cellular Longevity. 2013: 839409 |
| Keum YS. (2012) Regulation of Nrf2-Mediated Phase II Detoxification and Anti-oxidant Genes. Biomolecules & Therapeutics. 20: 144-51 |