Yuriy O. Alekseyev, Ph.D.

Affiliations: 
2001 Wayne State University, Detroit, MI, United States 
Area:
Biochemistry, Oncology
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"Yuriy Alekseyev"
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Louis James Romano grad student 2001 Wayne State
 (Translesional bypass of a bulky DNA adduct: Insights into the mechanism of chemical carcinogenesis.)
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Publications

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Podnar JW, Pantano L, Zeller MJ, et al. (2020) Cross-Site Evaluation of Commercial Sanger Sequencing Chemistries. Journal of Biomolecular Techniques : Jbt
Beane J, Vick J, Schembri F, et al. (2011) Characterizing the impact of smoking and lung cancer on the airway transcriptome using RNA-Seq. Cancer Prevention Research (Philadelphia, Pa.). 4: 803-17
Papageorgis P, Lambert AW, Ozturk S, et al. (2010) Smad signaling is required to maintain epigenetic silencing during breast cancer progression. Cancer Research. 70: 968-78
Neeley WL, Delaney S, Alekseyev YO, et al. (2007) DNA polymerase V allows bypass of toxic guanine oxidation products in vivo. The Journal of Biological Chemistry. 282: 12741-8
Alekseyev YO, Hamm ML, Essigmann JM. (2004) Aflatoxin B1 formamidopyrimidine adducts are preferentially repaired by the nucleotide excision repair pathway in vivo. Carcinogenesis. 25: 1045-51
Alekseyev YO, Romano LJ. (2002) Effects of benzo[a]pyrene adduct stereochemistry on downstream DNA replication in vitro: evidence for different adduct conformations within the active site of DNA polymerase I (Klenow fragment). Biochemistry. 41: 4467-79
Alekseyev YO, Dzantiev L, Romano LJ. (2001) Effects of benzo[a]pyrene DNA adducts on Escherichia coli DNA polymerase I (Klenow fragment) primer-template interactions: evidence for inhibition of the catalytically active ternary complex formation. Biochemistry. 40: 2282-90
Dzantiev L, Alekseyev YO, Morales JC, et al. (2001) Significance of nucleobase shape complementarity and hydrogen bonding in the formation and stability of the closed polymerase - DNA complex Biochemistry. 40: 3215-3221
Alekseyev YO, Romano LJ. (2000) In vitro replication of primer-templates containing benzo[a]pyrene adducts by exonuclease-deficient Escherichia coli DNA polymerase I (Klenow fragment): effect of sequence context on lesion bypass. Biochemistry. 39: 10431-8
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