Samer Lone, Ph.D.
Affiliations: | 2003 | Wayne State University, Detroit, MI, United States |
Area:
BiochemistryGoogle:
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Parents
Sign in to add mentorLouis James Romano | grad student | 2003 | Wayne State | |
(Altered DNA polymerase geometry: Implications for the mechanism of replication opposite bulky DNA adducts.) |
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Publications
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Chaurasiya KR, Ruslie C, Silva MC, et al. (2013) Polymerase manager protein UmuD directly regulates Escherichia coli DNA polymerase III α binding to ssDNA. Nucleic Acids Research. 41: 8959-68 |
Ummat A, Rechkoblit O, Jain R, et al. (2012) Structural basis for cisplatin DNA damage tolerance by human polymerase η during cancer chemotherapy. Nature Structural & Molecular Biology. 19: 628-32 |
Vasquez-Del Carpio R, Silverstein TD, Lone S, et al. (2011) Role of human DNA polymerase κ in extension opposite from a cis-syn thymine dimer. Journal of Molecular Biology. 408: 252-61 |
Vasquez-Del Carpio R, Silverstein TD, Lone S, et al. (2009) Structure of human DNA polymerase kappa inserting dATP opposite an 8-OxoG DNA lesion. Plos One. 4: e5766 |
Lone S, Townson SA, Uljon SN, et al. (2007) Human DNA polymerase kappa encircles DNA: implications for mismatch extension and lesion bypass. Molecular Cell. 25: 601-14 |
Lone S, Romano LJ. (2007) The role of specific amino acid residues in the active site of Escherichia coli DNA polymerase I on translesion DNA synthesis across from and past an N-2-aminofluorene adduct. Biochemistry. 46: 2599-607 |
Lone S, Romano LJ. (2003) Mechanistic insights into replication across from bulky DNA adducts: a mutant polymerase I allows an N-acetyl-2-aminofluorene adduct to be accommodated during DNA synthesis. Biochemistry. 42: 3826-34 |