Scott M. Severance, Ph.D.

Affiliations: 
2005 State University of New York, Buffalo, Buffalo, NY, United States 
Area:
Biochemistry
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"Scott Severance"
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Daniel J. Kosman grad student 2005 SUNY Buffalo
 (Analysis of the structure and function of the high affinity iron permease, Ftr1p, from Saccharomyces cerevisiae.)
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Publications

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Severance S, Rajagopal A, Rao AU, et al. (2010) Genome-wide analysis reveals novel genes essential for heme homeostasis in Caenorhabditis elegans. Plos Genetics. 6: e1001044
Severance S, Hamza I. (2009) Trafficking of heme and porphyrins in metazoa. Chemical Reviews. 109: 4596-616
Kwok EY, Severance S, Kosman DJ. (2006) Evidence for iron channeling in the Fet3p-Ftr1p high-affinity iron uptake complex in the yeast plasma membrane. Biochemistry. 45: 6317-27
Singh A, Severance S, Kaur N, et al. (2006) Assembly, activation, and trafficking of the Fet3p.Ftr1p high affinity iron permease complex in Saccharomyces cerevisiae. The Journal of Biological Chemistry. 281: 13355-64
Kwok EY, Stoj CS, Severance S, et al. (2006) An engineered bifunctional high affinity iron uptake protein in the yeast plasma membrane. Journal of Inorganic Biochemistry. 100: 1053-60
Severance S, Chakraborty S, Kosman DJ. (2004) The Ftr1p iron permease in the yeast plasma membrane: orientation, topology and structure-function relationships. The Biochemical Journal. 380: 487-96
Wang TP, Quintanar L, Severance S, et al. (2003) Targeted suppression of the ferroxidase and iron trafficking activities of the multicopper oxidase Fet3p from Saccharomyces cerevisiae. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 8: 611-20
Palmer AE, Quintanar L, Severance S, et al. (2002) Spectroscopic characterization and O2 reactivity of the trinuclear Cu cluster of mutants of the multicopper oxidase Fet3p. Biochemistry. 41: 6438-48
Machonkin TE, Quintanar L, Palmer AE, et al. (2001) Spectroscopy and reactivity of the type 1 copper site in Fet3p from Saccharomyces cerevisiae: correlation of structure with reactivity in the multicopper oxidases. Journal of the American Chemical Society. 123: 5507-17
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