Amy E. Moritz, Ph.D.
Affiliations: | 2011 | The University of North Dakota, Grand Forks, ND, United States |
Area:
BiochemistryGoogle:
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Parents
Sign in to add mentor| Roxanne A. Vaughan | grad student | 2011 | University of North Dakota | |
| (Post-translational regulation of the dopamine transporter.) | ||||
| David R. Sibley | post-doc | NIH (Neurotree) | ||
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Publications
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| Moritz AE, Bonifazi A, Guerrero AM, et al. (2020) Evidence for a stereoselective mechanism for bitopic activity by extended-length antagonists of the D3 dopamine receptor. Acs Chemical Neuroscience |
| Moritz AE, Free RB, Weiner WS, et al. (2020) Discovery, Optimization and Characterization of ML417: A Novel and Highly Selective D3 Dopamine Receptor Agonist. Journal of Medicinal Chemistry |
| Sanchez-Soto M, Verma RK, Willette BKA, et al. (2020) A structural basis for how ligand binding site changes can allosterically regulate GPCR signaling and engender functional selectivity. Science Signaling. 13 |
| Bolland DE, Moritz AE, Stanislowski DJ, et al. (2019) Palmitoylation by multiple DHHC enzymes enhances dopamine transporter function and stability. Acs Chemical Neuroscience |
| Chun LS, Vekariya RH, Free RB, et al. (2018) Structure-Activity Investigation of a G Protein-Biased Agonist Reveals Molecular Determinants for Biased Signaling of the DDopamine Receptor. Frontiers in Synaptic Neuroscience. 10: 2 |
| Moritz AE, Benjamin Free R, Sibley DR. (2017) Advances and challenges in the search for D2 and D3 dopamine receptor-selective compounds. Cellular Signalling |
| Kumar V, Moritz AE, Keck TM, et al. (2017) Synthesis and Pharmacological Characterization of Novel trans-Cyclopropylmethyl-Linked Bivalent Ligands That Exhibit Selectivity and Allosteric Pharmacology at the Dopamine D3 Receptor (D3R). Journal of Medicinal Chemistry |
| Moritz AE, Rastedt DE, Stanislowski DJ, et al. (2015) Reciprocal Phosphorylation and Palmitoylation Control Dopamine Transporter Kinetics. The Journal of Biological Chemistry |
| Meade JA, Free RB, Miller NR, et al. (2015) (-)-Stepholidine is a potent pan-dopamine receptor antagonist of both G protein- and β-arrestin-mediated signaling. Psychopharmacology. 232: 917-30 |
| Furman CA, Roof RA, Moritz AE, et al. (2014) Investigation of the binding and functional properties of extended length D3 dopamine receptor-selective antagonists. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology |