Suman Penugonda, Ph.D.

Affiliations: 
2006 University of Missouri-Rolla, Rolla, MO, United States 
Area:
Toxicology
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Nuran Ercal grad student 2006 University of Missouri-Rolla
 (Role of glutamate in lead -induced toxicity: Protection by n-acetylcysteine amide (NACA), a novel thiol antioxidant.)
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Publications

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Carey JW, Pinarci EY, Penugonda S, et al. (2011) In vivo inhibition of l-buthionine-(S,R)-sulfoximine-induced cataracts by a novel antioxidant, N-acetylcysteine amide. Free Radical Biology & Medicine. 50: 722-9
Penugonda S, Ercal N. (2011) Comparative evaluation of N-acetylcysteine (NAC) and N-acetylcysteine amide (NACA) on glutamate and lead-induced toxicity in CD-1 mice. Toxicology Letters. 201: 1-7
Penugonda S, Agarwal HK, Parang K, et al. (2010) Plasma pharmacokinetics and tissue disposition of novel dextran-methylprednisolone conjugates with peptide linkers in rats. Journal of Pharmaceutical Sciences. 99: 1626-37
Zhang SQ, Thorsheim HR, Penugonda S, et al. (2009) Liquid chromatography-tandem mass spectrometry for the determination of methylprednisolone in rat plasma and liver after intravenous administration of its liver-targeted dextran prodrug. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 877: 927-32
Penugonda S, Kumar A, Agarwal HK, et al. (2008) Synthesis and in vitro characterization of novel dextran-methylprednisolone conjugates with peptide linkers: effects of linker length on hydrolytic and enzymatic release of methylprednisolone and its peptidyl intermediates. Journal of Pharmaceutical Sciences. 97: 2649-64
Mare S, Penugonda S, Robinson SM, et al. (2007) Copper complexing decreases the ability of amyloid beta peptide to cross the BBB and enter brain parenchyma. Peptides. 28: 1424-32
Penugonda S, Mare S, Lutz P, et al. (2006) Potentiation of lead-induced cell death in PC12 cells by glutamate: protection by N-acetylcysteine amide (NACA), a novel thiol antioxidant. Toxicology and Applied Pharmacology. 216: 197-205
Penugonda S, Mare S, Goldstein G, et al. (2005) Effects of N-acetylcysteine amide (NACA), a novel thiol antioxidant against glutamate-induced cytotoxicity in neuronal cell line PC12. Brain Research. 1056: 132-8
Mare S, Penugonda S, Ercal N. (2005) High performance liquid chromatography analysis of MESNA (2-mercaptoethane sulfonate) in biological samples using fluorescence detection. Biomedical Chromatography : Bmc. 19: 80-6
Penugonda S, Wu W, Mare S, et al. (2004) Liquid chromatography analysis of N-(2-mercaptopropionyl)-glycine in biological samples by ThioGlo 3 derivatization. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 807: 251-6
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