Steven L. Ponicsan, Ph.D.

2012 Chemistry University of Colorado, Boulder, Boulder, CO, United States 
"Steven Ponicsan"
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James A. Goodrich grad student 2012 CU Boulder
 (Studies of the ncRNA binding site on RNA polymerase II and the sequence determinants of B2 RNA function as a repressor of transcription.)
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Ponicsan SL, Kugel JF, Goodrich JA. (2015) Repression of RNA Polymerase II Transcription by B2 RNA Depends on a Specific Pattern of Structural Regions in the RNA. Non-Coding Rna. 1: 4-16
Ponicsan SL, Houel S, Old WM, et al. (2013) The non-coding B2 RNA binds to the DNA cleft and active-site region of RNA polymerase II Journal of Molecular Biology. 425: 3625-3638
Wagner SD, Yakovchuk P, Gilman B, et al. (2013) RNA polymerase II acts as an RNA-dependent RNA polymerase to extend and destabilize a non-coding RNA. The Embo Journal. 32: 781-90
Dridi S, Hirano Y, Tarallo V, et al. (2012) ERK1/2 activation is a therapeutic target in age-related macular degeneration. Proceedings of the National Academy of Sciences of the United States of America. 109: 13781-6
Tarallo V, Hirano Y, Gelfand BD, et al. (2012) DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88. Cell. 149: 847-59
Kaneko H, Dridi S, Tarallo V, et al. (2011) DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration. Nature. 471: 325-30
Ponicsan SL, Kugel JF, Goodrich JA. (2010) Genomic gems: SINE RNAs regulate mRNA production Current Opinion in Genetics and Development. 20: 149-155
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