Carrie M. Mosher, Ph.D.

2008 University of Washington, Seattle, Seattle, WA 
Pharmacology, Biochemistry
"Carrie Mosher"
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Allan E. Rettie grad student 2008 University of Washington
 (CYP2C9 binding determinants and activation mechanisms for phenytoin and (S)-warfarin metabolism.)
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Bratton SM, Mosher CM, Khallouki F, et al. (2012) Analysis of R- and S-hydroxywarfarin glucuronidation catalyzed by human liver microsomes and recombinant UDP-glucuronosyltransferases. The Journal of Pharmacology and Experimental Therapeutics. 340: 46-55
Mosher CM, Court MH. (2010) Comparative and veterinary pharmacogenomics. Handbook of Experimental Pharmacology. 49-77
Mosher CM, Tai G, Rettie AE. (2009) CYP2C9 amino acid residues influencing phenytoin turnover and metabolite regio- and stereochemistry. The Journal of Pharmacology and Experimental Therapeutics. 329: 938-44
Mosher CM, Hummel MA, Tracy TS, et al. (2008) Functional analysis of phenylalanine residues in the active site of cytochrome P450 2C9. Biochemistry. 47: 11725-34
Hummel MA, Locuson CW, Gannett PM, et al. (2005) CYP2C9 genotype-dependent effects on in vitro drug-drug interactions: switching of benzbromarone effect from inhibition to activation in the CYP2C9.3 variant. Molecular Pharmacology. 68: 644-51
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