Oliver T. Parkinson, Ph.D.
Affiliations: | 2012 | Medicinal Chemistry | University of Washington, Seattle, Seattle, WA |
Area:
Biochemistry, ToxicologyGoogle:
"Oliver Parkinson"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Allan E. Rettie | grad student | 2012 | University of Washington | |
| (Species Differences in the Metabolism and Toxicity of 4-Ipomeanol.) | ||||
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| Teitelbaum AM, McDonald MG, Kowalski JP, et al. (2018) Influence of Stereochemistry on the Bioactivation and Glucuronidation of 4-Ipomeanol. The Journal of Pharmacology and Experimental Therapeutics |
| Parkinson OT, Teitelbaum AM, Whittington D, et al. (2016) Species Differences in Microsomal Oxidation and Glucuronidation of 4-Ipomeanol: Relationship to Target Organ Toxicity. Drug Metabolism and Disposition: the Biological Fate of Chemicals |
| Schmidt EM, Wiek C, Parkinson OT, et al. (2015) Characterization of an Additional Splice Acceptor Site Introduced into CYP4B1 in Hominoidae during Evolution. Plos One. 10: e0137110 |
| Haupt LJ, Kazmi F, Ogilvie BW, et al. (2015) The Reliability of Estimating Ki Values for Direct, Reversible Inhibition of Cytochrome P450 Enzymes from Corresponding IC50 Values: A Retrospective Analysis of 343 Experiments. Drug Metabolism and Disposition: the Biological Fate of Chemicals |
| Parkinson OT, Liggitt HD, Rettie AE, et al. (2013) Generation and characterization of a Cyp4b1 null mouse and the role of CYP4B1 in the activation and toxicity of Ipomeanol. Toxicological Sciences : An Official Journal of the Society of Toxicology. 134: 243-50 |
| Parkinson OT, Kelly EJ, Bezabih E, et al. (2012) Bioactivation of 4-Ipomeanol by a CYP4B enzyme in bovine lung and inhibition by HET0016. Journal of Veterinary Pharmacology and Therapeutics. 35: 402-5 |
| Wang MZ, Saulter JY, Usuki E, et al. (2006) CYP4F enzymes are the major enzymes in human liver microsomes that catalyze the O-demethylation of the antiparasitic prodrug DB289 [2,5-bis(4-amidinophenyl)furan-bis-O-methylamidoxime]. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 34: 1985-94 |