Florence Y. Lee, Ph.D.

Affiliations: 
2006 University of California, Los Angeles, Los Angeles, CA 
Area:
Cell Biology, Molecular Biology
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"Florence Lee"
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Peter A. Edwards grad student 2006 UCLA
 (Identification of novel physiological roles for the farnesoid X receptor.)
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Publications

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Lee FY, Faivre EJ, Suzawa M, et al. (2011) Eliminating SF-1 (NR5A1) sumoylation in vivo results in ectopic hedgehog signaling and disruption of endocrine development. Developmental Cell. 21: 315-27
Lee FY, de Aguiar Vallim TQ, Chong HK, et al. (2010) Activation of the farnesoid X receptor provides protection against acetaminophen-induced hepatic toxicity. Molecular Endocrinology (Baltimore, Md.). 24: 1626-36
Lee FY, de Aguiar Vallim TQ, Chong HK, et al. (2010) Activation of the Farnesoid X-Activated Receptor Provides Protection against Acetaminophen-Induced Hepatic Toxicity The Journal of Clinical Endocrinology & Metabolism. 95: 3563-3563
Kurrasch DM, Cheung CC, Lee FY, et al. (2007) The neonatal ventromedial hypothalamus transcriptome reveals novel markers with spatially distinct patterning. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 13624-34
Hubbert ML, Zhang Y, Lee FY, et al. (2007) Regulation of hepatic Insig-2 by the farnesoid X receptor. Molecular Endocrinology (Baltimore, Md.). 21: 1359-69
Lee FY, Lee H, Hubbert ML, et al. (2006) FXR, a multipurpose nuclear receptor. Trends in Biochemical Sciences. 31: 572-80
Zhang Y, Wang X, Vales C, et al. (2006) FXR deficiency causes reduced atherosclerosis in Ldlr-/- mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 2316-21
Zhang Y, Lee FY, Barrera G, et al. (2006) Activation of the nuclear receptor FXR improves hyperglycemia and hyperlipidemia in diabetic mice. Proceedings of the National Academy of Sciences of the United States of America. 103: 1006-11
Lee H, Zhang Y, Lee FY, et al. (2006) FXR regulates organic solute transporters alpha and beta in the adrenal gland, kidney, and intestine. Journal of Lipid Research. 47: 201-14
Lee FY, Kast-Woelbern HR, Chang J, et al. (2005) Alpha-crystallin is a target gene of the farnesoid X-activated receptor in human livers. The Journal of Biological Chemistry. 280: 31792-800
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