Jason S. Fisk, Ph.D.

Affiliations: 
2009 Michigan State University, East Lansing, MI 
Area:
Organic Chemistry, Pharmaceutical Chemistry
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Jetze J. Tepe grad student 2009 Michigan State
 (Syntheses of alpha,alpha-disubstituted-alpha-amino acids and imidazolines derived from oxazol -5(4H) -ones.)
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Azevedo LM, Lansdell TA, Ludwig JR, et al. (2013) Inhibition of the human proteasome by imidazoline scaffolds. Journal of Medicinal Chemistry. 56: 5974-8
Qu K, Fisk JS, Tepe JJ. (2011) Azomethine ylide mediated inversion of configuration of quaternary imidazoline carbon: converting trans- to its cis- imidazolines. Tetrahedron Letters. 52: 4840-4842
Kahlon DK, Lansdell TA, Fisk JS, et al. (2009) Structural-activity relationship study of highly-functionalized imidazolines as potent inhibitors of nuclear transcription factor-kappaB mediated IL-6 production. Bioorganic & Medicinal Chemistry. 17: 3093-103
Kahlon DK, Lansdell TA, Fisk JS, et al. (2009) Nuclear factor-κB mediated inhibition of cytokine production by imidazoline scaffolds Journal of Medicinal Chemistry. 52: 1302-1309
Mosey RA, Fisk JS, Tepe JJ. (2009) ChemInform Abstract: Stereoselective Syntheses of Quaternary Substituted α-Amino Acids Using Oxazol-5-(4H)-ones Cheminform. 40
Mosey RA, Fisk JS, Friebe TL, et al. (2008) Synthesis of tert-alkyl amino hydroxy carboxylic esters via an intermolecular ene-type reaction of oxazolones and enol ethers. Organic Letters. 10: 825-8
Mosey RA, Fisk JS, Tepe JJ. (2008) Stereoselective syntheses of quaternary substituted α-amino acids using oxazol-5-(4H)-ones Tetrahedron Asymmetry. 19: 2755-2762
Fisk JS, Mosey RA, Tepe JJ. (2007) The diverse chemistry of oxazol-5-(4H)-ones. Chemical Society Reviews. 36: 1432-40
Fisk JS, Tepe JJ. (2007) Intermolecular ene reactions utilizing oxazolones and enol ethers. Journal of the American Chemical Society. 129: 3058-9
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