Kelly Ruggles, Ph.D.

Affiliations: 
2012 Nutritional and Metabolic Biology Columbia University, New York, NY 
Area:
Nutrition, Cell Biology
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"Kelly Ruggles"
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Stephen L. Sturley grad student 2012 Columbia
 (Cellular Fatty Acid Toxicity: Extrapolating Yeast Screens into Mammalian Models.)
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Publications

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Conlon DM, Thomas T, Fedotova T, et al. (2016) Inhibition of apolipoprotein B synthesis stimulates endoplasmic reticulum autophagy that prevents steatosis. The Journal of Clinical Investigation
Gulati S, Ekland EH, Ruggles KV, et al. (2015) Profiling the Essential Nature of Lipid Metabolism in Asexual Blood and Gametocyte Stages of Plasmodium falciparum. Cell Host & Microbe. 18: 371-81
Gulati S, Balderes D, Kim C, et al. (2015) ATP-binding cassette transporters and sterol O-acyltransferases interact at membrane microdomains to modulate sterol uptake and esterification. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology
Ruggles KV, Garbarino J, Liu Y, et al. (2014) A functional, genome-wide evaluation of liposensitive yeast identifies the "ARE2 required for viability" (ARV1) gene product as a major component of eukaryotic fatty acid resistance. The Journal of Biological Chemistry. 289: 4417-31
Nilsson CL, Vegvari A, Mostovenko E, et al. (2014) SC-23 * THE ROLE OF SINGLE AMINO ACID POLYMORPHISMS IN GLIOMA STEM CELL PHENOTYPES Neuro-Oncology. 16: v202-v202
Ruggles KV, Turkish A, Sturley SL. (2013) Making, baking, and breaking: the synthesis, storage, and hydrolysis of neutral lipids. Annual Review of Nutrition. 33: 413-51
Fakas S, Qiu Y, Dixon JL, et al. (2011) Phosphatidate phosphatase activity plays key role in protection against fatty acid-induced toxicity in yeast. The Journal of Biological Chemistry. 286: 29074-85
Fakas S, Qiu Y, Dixon J, et al. (2011) PAH1-encoded phosphatidate phosphatase activity plays an essential role in protecting yeast against fatty acid-induced toxicity Chemistry and Physics of Lipids. 164: S10
Garbarino J, Padamsee M, Wilcox L, et al. (2009) Sterol and diacylglycerol acyltransferase deficiency triggers fatty acid-mediated cell death. The Journal of Biological Chemistry. 284: 30994-1005
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