Angela K. Deem, Ph.D.

Affiliations: 
2011 Biological Sciences Purdue University, West Lafayette, IN, United States 
Area:
Genetics
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"Angela Deem"
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Parents

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Cynthia V. Stauffacher grad student 2011 Purdue
 (Genome-destabilizing and mutagenic effects of break-induced replication in Saccharomyces cerevisiae.)
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Publications

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Puca F, Yu F, Bartolacci C, et al. (2021) Medium-chain acyl CoA dehydrogenase protects mitochondria from lipid peroxidation in glioblastoma. Cancer Discovery
Inoue A, Robinson FS, Minelli R, et al. (2021) Sequential administration of XPO1 and ATR inhibitors enhances therapeutic response in TP53-mutated colorectal cancer. Gastroenterology
Tomihara H, Carbone F, Perelli L, et al. (2020) Loss of ARID1A promotes epithelial-mesenchymal transition and sensitizes pancreatic tumors to proteotoxic stress. Cancer Research
Citron F, Perelli L, Deem AK, et al. (2020) Leukotrienes, a potential target for Covid-19. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 161: 102174
Loponte S, Lovisa S, Deem AK, et al. (2019) The Many Facets of Tumor Heterogeneity: Is Metabolism Lagging Behind? Cancers. 11
Inoue A, Deem AK, Kopetz S, et al. (2019) Current and Future Horizons of Patient-Derived Xenograft Models in Colorectal Cancer Translational Research. Cancers. 11
Yao W, Rose JL, Wang W, et al. (2019) Syndecan 1 is a critical mediator of macropinocytosis in pancreatic cancer. Nature
Sakofsky CJ, Ayyar S, Deem AK, et al. (2015) Translesion Polymerases Drive Microhomology-Mediated Break-Induced Replication Leading to Complex Chromosomal Rearrangements. Molecular Cell
Pettazzoni P, Viale A, Shah P, et al. (2015) Genetic events that limit the efficacy of MEK and RTK inhibitor therapies in a mouse model of KRAS-driven pancreatic cancer. Cancer Research. 75: 1091-101
Viale A, Pettazzoni P, Lyssiotis CA, et al. (2014) Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function. Nature. 514: 628-32
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