Yogesh A. Sabnis, Ph.D.
Affiliations: | 2002 | The University of Mississippi, USA |
Area:
Pharmaceutical ChemistryGoogle:
"Yogesh Sabnis"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Mitchell Allen Avery | grad student | 2002 | The University of Mississippi | |
| (Modeling, design and synthesis of parasitic cysteine protease inhibitors.) | ||||
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Publications
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| Jones P, Storer RI, Sabnis YA, et al. (2016) Design and Synthesis of a pan-Janus Kinase Inhibitor Clinical Candidate (PF-06263276) Suitable for Inhaled and Topical Delivery for the Treatment of Inflammatory Diseases of the Lungs and Skin. Journal of Medicinal Chemistry |
| Liu Q, Sabnis Y, Zhao Z, et al. (2013) Developing irreversible inhibitors of the protein kinase cysteinome. Chemistry & Biology. 20: 146-59 |
| Lovering F, McDonald J, Whitlock GA, et al. (2012) Identification of type-II inhibitors using kinase structures. Chemical Biology & Drug Design. 80: 657-64 |
| Miller DC, Lunn G, Jones P, et al. (2012) Investigation of the effect of molecular properties on the binding kinetics of a ligand to its biological target Medchemcomm. 3: 449 |
| Muthas D, Sabnis YA, Lundborg M, et al. (2008) Is it possible to increase hit rates in structure-based virtual screening by pharmacophore filtering? An investigation of the advantages and pitfalls of post-filtering. Journal of Molecular Graphics & Modelling. 26: 1237-51 |
| Rönn R, Gossas T, Sabnis YA, et al. (2007) Evaluation of a diverse set of potential P1 carboxylic acid bioisosteres in hepatitis C virus NS3 protease inhibitors. Bioorganic & Medicinal Chemistry. 15: 4057-68 |
| Ortqvist P, Peterson SD, Kerblom E, et al. (2007) Phenylglycine as a novel P2 scaffold in hepatitis C virus NS3 protease inhibitors. Bioorganic & Medicinal Chemistry. 15: 1448-74 |
| Wannberg J, Sabnis YA, Vrang L, et al. (2006) A new structural theme in C2-symmetric HIV-1 protease inhibitors: ortho-substituted P1/P1' side chains. Bioorganic & Medicinal Chemistry. 14: 5303-15 |
| Rönn R, Sabnis YA, Gossas T, et al. (2006) Exploration of acyl sulfonamides as carboxylic acid replacements in protease inhibitors of the hepatitis C virus full-length NS3. Bioorganic & Medicinal Chemistry. 14: 544-59 |
| Muthas D, Nöteberg D, Sabnis YA, et al. (2005) Synthesis, biological evaluation, and modeling studies of inhibitors aimed at the malarial proteases plasmepsins I and II. Bioorganic & Medicinal Chemistry. 13: 5371-90 |