Glen C. Post, Ph.D.

Affiliations: 
2006 University of Colorado, Boulder, Boulder, CO, United States 
Area:
Organic Chemistry, Pharmaceutical Chemistry
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Tad Harbison Koch grad student 2006 CU Boulder
 (Design, synthesis, and biological evaluation of anthracycline-formaldehyde conjugates.)
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Publications

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Koch TH, Barthel BL, Kalet BT, et al. (2008) Anthracycline-formaldehyde conjugates and their targeted prodrugs. Topics in Current Chemistry. 283: 141-70
Spencer DM, Bilardi RA, Koch TH, et al. (2008) DNA repair in response to anthracycline-DNA adducts: a role for both homologous recombination and nucleotide excision repair. Mutation Research. 638: 110-21
Burkhart DJ, Barthel BL, Post GC, et al. (2006) Design, synthesis, and preliminary evaluation of doxazolidine carbamates as prodrugs activated by carboxylesterases. Journal of Medicinal Chemistry. 49: 7002-12
Post GC, Barthel BL, Burkhart DJ, et al. (2005) Doxazolidine, a proposed active metabolite of doxorubicin that cross-links DNA. Journal of Medicinal Chemistry. 48: 7648-57
Burkhart DJ, Kalet BT, Coleman MP, et al. (2004) Doxorubicin-formaldehyde conjugates targeting alphavbeta3 integrin. Molecular Cancer Therapeutics. 3: 1593-604
Cogan P, Fowler C, Post G, et al. (2004) Doxsaliform: A Novel N-Mannich Base Prodrug of a Doxorubicin Formaldehyde Conjugate Letters in Drug Design & Discovery. 1: 247-255
Kato S, Post GC, Bierbaum VM, et al. (2002) Chemical ionization mass spectrometric determination of acrolein in human breast cancer cells. Analytical Biochemistry. 305: 251-9
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