Phillip H. Abbosh, Ph.D.

Affiliations: 
2006 Indiana University, Bloomington, Bloomington, IN, United States 
Area:
Cell Biology, Molecular Biology, Biochemistry
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"Phillip Abbosh"
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Parents

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Kenneth P. Nephew grad student 2006 Indiana University Bloomington
 (Novel approaches to treat undifferentiated thyroid cancers: Gene therapy targeting dedifferentiation and epigenetic reprogramming.)
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Publications

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Gokare P, Finnberg NK, Abbosh PH, et al. (2017) P53 represses pyrimidine catabolic gene dihydropyrimidine dehydrogenase (DPYD) expression in response to thymidylate synthase (TS) targeting. Scientific Reports. 7: 9711
Abbosh PH, Zhang S, Maclennan GT, et al. (2008) Germ cell origin of testicular carcinoid tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 1393-6
Abbosh PH, Wang M, Eble JN, et al. (2008) Hypermethylation of tumor-suppressor gene CpG islands in small-cell carcinoma of the urinary bladder. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 21: 355-62
Abbosh PH, Li X, Li L, et al. (2007) A conditionally replicative, Wnt/beta-catenin pathway-based adenovirus therapy for anaplastic thyroid cancer. Cancer Gene Therapy. 14: 399-408
Fan M, Yan PS, Hartman-Frey C, et al. (2006) Diverse gene expression and DNA methylation profiles correlate with differential adaptation of breast cancer cells to the antiestrogens tamoxifen and fulvestrant. Cancer Research. 66: 11954-66
Abbosh PH, Montgomery JS, Starkey JA, et al. (2006) Dominant-negative histone H3 lysine 27 mutant derepresses silenced tumor suppressor genes and reverses the drug-resistant phenotype in cancer cells. Cancer Research. 66: 5582-91
Abbosh PH, Nephew KP. (2005) Multiple signaling pathways converge on beta-catenin in thyroid cancer. Thyroid : Official Journal of the American Thyroid Association. 15: 551-61
Abbosh PH, Nephew KP. (2004) 452. Adenoviral Gene Therapy Using CRAd Targeted to Cells with Hyperactive Wnt/|[beta]|-Catenin Signaling Molecular Therapy. 9
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