Brandon R. Goblirsch, Ph.D.

Affiliations: 
2011 Biochemistry, Molecular Bio, and Biophysics University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Biochemistry, General Biophysics, Molecular Chemistry
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"Brandon Goblirsch"
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Carrie M. Wilmot grad student 2011 UMN
 (X-Ray Crystallographic Studies Reveal Essential Structural Features of Specialized Microbial Enzymes: Molecular Oxygen Production by the Heme Dependent Enzyme Chlorite Dismutase and Fatty Acid Condensation by the Olefin Biosynthesis Enzyme OleA.)
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Publications

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Jensen MR, Goblirsch BR, Esler MA, et al. (2018) The role of OleA His285 in orchestration of long-chain acyl-coenzyme A substrates. Febs Letters
Jensen MR, Goblirsch BR, Christenson JK, et al. (2017) OleA Glu117 is key to condensation of two fatty-acyl coenzyme A substrates in long-chain olefin biosynthesis. The Biochemical Journal
Christenson JK, Jensen MR, Goblirsch BR, et al. (2017) Active Multi-Enzyme Assemblies for Long-Chain Olefinic Hydrocarbon Biosynthesis. Journal of Bacteriology
Goblirsch BR, Jensen MR, Mohamed F, et al. (2016) Substrate Trapping in Crystals of the Thiolase OleA Identifies Three Channels that Enable Long-Chain Olefin Biosynthesis. The Journal of Biological Chemistry
da Silva GF, Goblirsch BR, Tsai AL, et al. (2015) Cation-Specific Conformations in a Dual-Function Ion-Pumping Microbial Rhodopsin. Biochemistry. 54: 3950-9
Goblirsch BR, Frias JA, Wackett LP, et al. (2012) Crystal structures of Xanthomonas campestris OleA reveal features that promote head-to-head condensation of two long-chain fatty acids. Biochemistry. 51: 4138-46
Yukl ET, Goblirsch BR, Davidson VL, et al. (2011) Crystal structures of CO and NO adducts of MauG in complex with pre-methylamine dehydrogenase: implications for the mechanism of dioxygen activation. Biochemistry. 50: 2931-8
Goblirsch B, Kurker RC, Streit BR, et al. (2011) Chlorite dismutases, DyPs, and EfeB: 3 microbial heme enzyme families comprise the CDE structural superfamily. Journal of Molecular Biology. 408: 379-98
Frias JA, Goblirsch BR, Wackett LP, et al. (2010) Cloning, purification, crystallization and preliminary X-ray diffraction of the OleC protein from Stenotrophomonas maltophilia involved in head-to-head hydrocarbon biosynthesis. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1108-10
Goblirsch BR, Streit BR, Dubois JL, et al. (2010) Structural features promoting dioxygen production by Dechloromonas aromatica chlorite dismutase. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 15: 879-88
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