Valerie J. Klema, Ph.D.

Affiliations: 
2012 Biochemistry, Molecular Bio, and Biophysics University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Biochemistry
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"Valerie Klema"
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Parents

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Carrie M. Wilmot grad student 2012 UMN
 (Toward a Mechanistic Understanding of Cofactor Biogenesis and Catalysis in Copper Amine Oxidases from Hansenula polymorpha.)
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Publications

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Tu X, Latham JA, Klema VJ, et al. (2017) Crystal structures reveal metal-binding plasticity at the metallo-β-lactamase active site of PqqB from Pseudomonas putida. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry
Johnson BJ, Yukl ET, Klema VJ, et al. (2013) Structural snapshots from the oxidative half-reaction of a copper amine oxidase: Implications for O2 activation Journal of Biological Chemistry. 288: 28409-28417
Klema VJ, Solheid CJ, Klinman JP, et al. (2013) Structural analysis of aliphatic versus aromatic substrate specificity in a copper amine oxidase from hansenula polymorpha Biochemistry. 52: 2291-2301
Johnson BJ, Yukl ET, Klema VJ, et al. (2013) Structural evidence for the semiquinone in a copper amine oxidase from Hansenula polymorpha: implications for the catalytic mechanism Journal of Biological Chemistry
Klema VJ, Wilmot CM. (2012) The role of protein crystallography in defining the mechanisms of biogenesis and catalysis in copper amine oxidase. International Journal of Molecular Sciences. 13: 5375-405
Klema VJ, Johnson BJ, Klinman JP, et al. (2012) The precursor form of Hansenula polymorpha copper amine oxidase 1 in complex with Cu I and Co II Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 68: 501-510
Chang CM, Klema VJ, Johnson BJ, et al. (2010) Kinetic and structural analysis of substrate specificity in two copper amine oxidases from Hansenula polymorpha Biochemistry. 49: 2540-2550
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