Jose D. Otero-Cruz, Ph.D.

Affiliations: 
2008 University of Puerto Rico, Rio Piedras (Puerto Rico) 
Area:
Neuroscience Biology
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"Jose Otero-Cruz"
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Jose A. Lasalde-Dominicci grad student 2008 University of Puerto Rico, Rio Piedras (Puerto Rico)
 (The role of the alpha-M3 transmembrane domain and structural predictions of the lipid-exposed transmembrane domains of the nicotinic acetylcholine receptor.)
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Publications

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Báez-Pagán CA, Del Hoyo-Rivera N, Quesada O, et al. (2016) Heterogeneous Inhibition in Macroscopic Current Responses of Four Nicotinic Acetylcholine Receptor Subtypes by Cholesterol Enrichment. The Journal of Membrane Biology
Caballero-Rivera D, Cruz-Nieves OA, Oyola-Cintrón J, et al. (2012) Tryptophan scanning mutagenesis reveals distortions in the helical structure of the δM4 transmembrane domain of the Torpedo californica nicotinic acetylcholine receptor. Channels (Austin, Tex.). 6: 111-23
Caballero-Rivera D, Cruz-Nieves OA, Oyola-Cintrón J, et al. (2012) Tryptophan scanning mutagenesis reveals distortions in the helical structure of the δM4 transmembrane domain of the Torpedo californica nicotinic acetylcholine receptor Channels. 6
Caballero-Rivera D, Cruz-Nieves OA, Oyola-Cintrón J, et al. (2011) Fourier transform coupled tryptophan scanning mutagenesis identifies a bending point on the lipid-exposed δM3 transmembrane domain of the Torpedo californica nicotinic acetylcholine receptor. Channels (Austin, Tex.). 5: 345-56
Caballero-Rivera D, Cruz-Nieves OA, Oyola-Cintrón J, et al. (2011) Fourier transform coupled tryptophan scanning mutagenesis identifies a bending point on the lipid-exposed δM3 transmembrane domain of the Torpedo californica nicotinic acetylcholine receptor Channels. 5
Otero-Cruz JD, Báez-Pagán CA, Dorna-Pérez L, et al. (2010) Decoding pathogenesis of slow-channel congenital myasthenic syndromes using recombinant expression and mice models. Puerto Rico Health Sciences Journal. 29: 4-17
Díaz-De León R, Otero-Cruz JD, Torres-Nuñez DA, et al. (2008) Tryptophan scanning of the acetylcholine receptor's betaM4 transmembrane domain: decoding allosteric linkage at the lipid-protein interface with ion-channel gating. Channels (Austin, Tex.). 2: 439-48
Báez-Pagán CA, Martínez-Ortiz Y, Otero-Cruz JD, et al. (2008) Potential role of caveolin-1-positive domains in the regulation of the acetylcholine receptor's activatable pool: implications in the pathogenesis of a novel congenital myasthenic syndrome. Channels (Austin, Tex.). 2: 180-90
Otero-Cruz JD, Torres-Núñez DA, Báez-Pagán CA, et al. (2008) Fourier transform coupled to tryptophan-scanning mutagenesis: lessons from its application to the prediction of secondary structure in the acetylcholine receptor lipid-exposed transmembrane domains. Biochimica Et Biophysica Acta. 1784: 1200-7
Otero-Cruz JD, Báez-Pagán CA, Caraballo-González IM, et al. (2007) Tryptophan-scanning mutagenesis in the alphaM3 transmembrane domain of the muscle-type acetylcholine receptor. A spring model revealed. The Journal of Biological Chemistry. 282: 9162-71
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