Mark L. McCleland, Ph.D.

2004 University of Virginia, Charlottesville, VA 
Cell Biology
"Mark McCleland"
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Peter Todd Stukenberg grad student 2004 UVA
 (Understanding chromosome segregation: Functional analysis of the vertebrate Ndc80/Hec1 and Clip-170 kinetochore complexes.)
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Emanuele MJ, McCleland ML, Satinover DL, et al. (2005) Measuring the stoichiometry and physical interactions between components elucidates the architecture of the vertebrate kinetochore. Molecular Biology of the Cell. 16: 4882-92
McCleland ML, Stukenberg PT. (2005) Purification of the Ndc80 kinetochore subcomplex from Xenopus eggs. Methods in Molecular Biology (Clifton, N.J.). 296: 383-91
McCleland ML, Kallio MJ, Barrett-Wilt GA, et al. (2004) The vertebrate Ndc80 complex contains Spc24 and Spc25 homologs, which are required to establish and maintain kinetochore-microtubule attachment. Current Biology : Cb. 14: 131-7
McCleland ML, Gardner RD, Kallio MJ, et al. (2003) The highly conserved Ndc80 complex is required for kinetochore assembly, chromosome congression, and spindle checkpoint activity. Genes & Development. 17: 101-14
Bolton MA, Lan W, Powers SE, et al. (2002) Aurora B kinase exists in a complex with survivin and INCENP and its kinase activity is stimulated by survivin binding and phosphorylation. Molecular Biology of the Cell. 13: 3064-77
Kallio MJ, McCleland ML, Stukenberg PT, et al. (2002) Inhibition of aurora B kinase blocks chromosome segregation, overrides the spindle checkpoint, and perturbs microtubule dynamics in mitosis. Current Biology : Cb. 12: 900-5
Ficarro SB, McCleland ML, Stukenberg PT, et al. (2002) Phosphoproteome analysis by mass spectrometry and its application to Saccharomyces cerevisiae. Nature Biotechnology. 20: 301-5
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