Weihe Zhang, Ph.D.
Affiliations: | 2010 | Department of Chemistry and Biochemistry | Ohio University, Athens, OH, United States |
Area:
Organic Chemistry, BiochemistryGoogle:
"Weihe Zhang"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Stephen C. Bergmeier | grad student | 2010 | Ohio University | |
| (Design and Synthesis of Potential Anticancer Agents.) | ||||
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Publications
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| Zheng H, Zhao J, Li B, et al. (2021) UNC5293, a potent, orally available and highly MERTK-selective inhibitor. European Journal of Medicinal Chemistry. 220: 113534 |
| Roberts DA, Wang L, Zhang W, et al. (2020) Isosteres of ester derived glucose uptake inhibitors. Bioorganic & Medicinal Chemistry Letters. 30: 127406 |
| Wong JP, Stuhlmiller TJ, Giffin LC, et al. (2019) Kinome profiling of non-Hodgkin lymphoma identifies Tyro3 as a therapeutic target in primary effusion lymphoma. Proceedings of the National Academy of Sciences of the United States of America |
| Zhao J, Zhang D, Zhang W, et al. (2018) Highly selective MERTK inhibitors achieved by a single methyl group. Journal of Medicinal Chemistry |
| McIver A, Zhang W, Liu Q, et al. (2016) Discovery of Macrocyclic Pyrimidines as MerTK-specific Inhibitors. Chemmedchem |
| Wang X, Liu J, Zhang W, et al. (2016) Design and Synthesis of Novel Macrocyclic Mer Tyrosine Kinase Inhibitors. Acs Medicinal Chemistry Letters. 7: 1044-1049 |
| DeRyckere D, Lee Sherick AB, Huey MG, et al. (2016) UNC2025, a MerTK small molecule inhibitor, is therapeutically effective alone and in combination with methotrexate in leukemia models. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research |
| Minson KA, Smith CC, DeRyckere D, et al. (2016) The MERTK/FLT3 inhibitor MRX-2843 overcomes resistance-conferring FLT3 mutations in acute myeloid leukemia. Jci Insight. 1: e85630 |
| Cummings CT, Zhang W, Davies KD, et al. (2015) Small molecule inhibition of MERTK is efficacious in non-small cell lung cancer models independent of driver oncogene status. Molecular Cancer Therapeutics |
| Lee-Sherick AB, Zhang W, Menachof KK, et al. (2015) Efficacy of a Mer and Flt3 tyrosine kinase small molecule inhibitor, UNC1666, in acute myeloid leukemia. Oncotarget. 6: 6722-36 |