Laith Q. Al-Mawsawi, Ph.D.
Affiliations: | 2007 | Pharmaceutical Sciences | University of Southern California, Los Angeles, CA, United States |
Area:
Pharmacology, BiochemistryGoogle:
"Laith Al-Mawsawi"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Nouri Neamati | grad student | 2007 | USC | |
| (Discovery of a novel HIV -1 integrase inhibitor binding site: Insight into enzyme structure/function and inhibitor design.) | ||||
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Publications
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| Al-Mawsawi LQ, Wu NC, Olson CA, et al. (2014) High-throughput profiling of point mutations across the HIV-1 genome. Retrovirology. 11: 124 |
| Al-Mawsawi LQ, Wu NC, De La Cruz J, et al. (2014) Short communication: HIV-1 gag genetic variation in a single acutely infected participant defined by high-resolution deep sequencing. Aids Research and Human Retroviruses. 30: 806-11 |
| Qi H, Olson CA, Wu NC, et al. (2014) A quantitative high-resolution genetic profile rapidly identifies sequence determinants of hepatitis C viral fitness and drug sensitivity. Plos Pathogens. 10: e1004064 |
| Serrao E, Thys W, Demeulemeester J, et al. (2012) A symmetric region of the HIV-1 integrase dimerization interface is essential for viral replication. Plos One. 7: e45177 |
| Al-Mawsawi LQ, Neamati N. (2011) Allosteric inhibitor development targeting HIV-1 integrase. Chemmedchem. 6: 228-41 |
| Al-Mawsawi LQ, Neamati N. (2011) New Paradigm for Integrase Inhibition: Blocking Enzyme Function without Directly Targeting the Active Site Hiv-1 Integrase: Mechanism and Inhibitor Design. 457-476 |
| Debnath B, Al-Mawsawi LQ, Neamati N. (2010) Are we living in the end of the blockbuster drug era? Drug News & Perspectives. 23: 670-84 |
| Al-Mawsawi LQ, Al-Safi RI, Neamati N. (2008) Anti-infectives: clinical progress of HIV-1 integrase inhibitors. Expert Opinion On Emerging Drugs. 13: 213-25 |
| Al-Mawsawi LQ, Hombrouck A, Dayam R, et al. (2008) Four-tiered π interaction at the dimeric interface of HIV-1 integrase critical for DNA integration and viral infectivity Virology. 377: 355-363 |
| Al-Mawsawi LQ, Christ F, Dayam R, et al. (2008) Inhibitory profile of a LEDGF/p75 peptide against HIV-1 integrase: Insight into integrase-DNA complex formation and catalysis Febs Letters. 582: 1425-1430 |