Melissa Millard, Ph.D.

Affiliations: 
2013 Pharmaceutical Sciences University of Southern California, Los Angeles, CA, United States 
Area:
Pharmacy, Pharmacology, Oncology
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"Melissa Millard"
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Parents

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Nouri Neamati grad student 2013 USC
 (Discovery of novel small molecules targeting cancer cell metabolism.)
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Publications

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Millard M, Gallagher JD, Olenyuk BZ, et al. (2013) A selective mitochondrial-targeted chlorambucil with remarkable cytotoxicity in breast and pancreatic cancers. Journal of Medicinal Chemistry. 56: 9170-9
Ji Y, Majumder S, Millard M, et al. (2013) In vivo activation of the p53 tumor suppressor pathway by an engineered cyclotide. Journal of the American Chemical Society. 135: 11623-33
Shabaik YH, Millard M, Neamati N. (2013) Mechanistic evaluation of a novel small molecule targeting mitochondria in pancreatic cancer cells. Plos One. 8: e54346
Millard M, Odde S, Neamati N. (2011) Integrin targeted therapeutics. Theranostics. 1: 154-88
Yamada R, Cao X, Butkevich AN, et al. (2011) Discovery and preclinical evaluation of a novel class of cytotoxic propynoic acid carbamoyl methyl amides (PACMAs). Journal of Medicinal Chemistry. 54: 2902-14
Millard M, Pathania D, Grande F, et al. (2011) Small-molecule inhibitors of p53-MDM2 interaction: the 2006-2010 update. Current Pharmaceutical Design. 17: 536-59
Millard M, Pathania D, Shabaik Y, et al. (2010) Preclinical evaluation of novel triphenylphosphonium salts with broad-spectrum activity. Plos One. 5
Xu J, Millard M, Ren X, et al. (2010) c-Abl mediates endothelial apoptosis induced by inhibition of integrins alphavbeta3 and alphavbeta5 and by disruption of actin. Blood. 115: 2709-18
Pathania D, Millard M, Neamati N. (2009) Opportunities in discovery and delivery of anticancer drugs targeting mitochondria and cancer cell metabolism. Advanced Drug Delivery Reviews. 61: 1250-75
Erdreich-Epstein A, Tran LB, Cox OT, et al. (2005) Endothelial apoptosis induced by inhibition of integrins alphavbeta3 and alphavbeta5 involves ceramide metabolic pathways. Blood. 105: 4353-61
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