Natura Myeku, Ph.D.
Affiliations: | 2011 | Biology | City University of New York, New York, NY, United States |
Area:
Molecular Biology, Cell Biology, Neuroscience BiologyGoogle:
"Natura Myeku"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Maria Figueiredo-Pereira | grad student | 2011 | CUNY | |
| (Ubiquitin proteasome pathway, autophagy and a novel therapeutic approach to prevent neurodegeneration linked to inflammation in ALS.) | ||||
| Karen Duff | post-doc | Columbia University Irving Medical Center (Neurotree) | ||
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Publications
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| Schaler AW, Runyan AM, Clelland CL, et al. (2021) PAC1 receptor-mediated clearance of tau in postsynaptic compartments attenuates tau pathology in mouse brain. Science Translational Medicine. 13 |
| Myeku N, Duff KE. (2017) Targeting the 26S Proteasome To Protect Against Proteotoxic Diseases. Trends in Molecular Medicine |
| Schaler AW, Myeku N. (2017) Cilostazol, a phosphodiesterase 3 inhibitor, activates proteasome proteolysis and attenuates tauopathy and cognitive decline. Translational Research : the Journal of Laboratory and Clinical Medicine |
| Myeku N, Clelland CL, Emrani S, et al. (2015) Tau-driven 26S proteasome impairment and cognitive dysfunction can be prevented early in disease by activating cAMP-PKA signaling. Nature Medicine |
| Myeku N, Wang H, Figueiredo-Pereira ME. (2012) cAMP stimulates the ubiquitin/proteasome pathway in rat spinal cord neurons. Neuroscience Letters. 527: 126-31 |
| Congdon EE, Wu JW, Myeku N, et al. (2012) Methylthioninium chloride (methylene blue) induces autophagy and attenuates tauopathy in vitro and in vivo. Autophagy. 8: 609-22 |
| Myeku N, Yu WH, Duff K. (2012) O4-11-03: Interaction between the ubiquitin proteasome system, autophagy and progressive tauopathy in vivo Alzheimer's & Dementia. 8: P636-P637 |
| Myeku N, Metcalfe MJ, Huang Q, et al. (2011) Assessment of proteasome impairment and accumulation/aggregation of ubiquitinated proteins in neuronal cultures. Methods in Molecular Biology (Clifton, N.J.). 793: 273-96 |
| Myeku N, Figueiredo-Pereira ME. (2011) Dynamics of the degradation of ubiquitinated proteins by proteasomes and autophagy: association with sequestosome 1/p62. The Journal of Biological Chemistry. 286: 22426-40 |
| Boamah EK, Brekman A, Tomasz M, et al. (2010) DNA adducts of decarbamoyl mitomycin C efficiently kill cells without wild-type p53 resulting from proteasome-mediated degradation of checkpoint protein 1. Chemical Research in Toxicology. 23: 1151-62 |