Paul L. Shaffer, Ph.D.
Affiliations: | 2005 | Duke University, Durham, NC |
Area:
Biochemistry, Molecular BiologyGoogle:
"Paul Shaffer"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Daniel T. Gewirth | grad student | 2005 | Duke | |
| (Structural studies of steroid and nuclear hormone receptors bound to DNA.) | ||||
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Publications
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| Diaz E, Adhikary S, Tepper AWJW, et al. (2022) Structure of human spermine oxidase in complex with a highly selective allosteric inhibitor. Communications Biology. 5: 787 |
| Huang X, Chen H, Shaffer PL. (2017) Crystal Structures of Human GlyRα3 Bound to Ivermectin. Structure (London, England : 1993) |
| Huang X, Chen H, Michelsen K, et al. (2015) Crystal structure of human glycine receptor-α3 bound to antagonist strychnine. Nature |
| Shaffer PL, McDonnell DP, Gewirth DT. (2005) Characterization of transcriptional activation and DNA-binding functions in the hinge region of the vitamin D receptor. Biochemistry. 44: 2678-85 |
| Immormino RM, Dollins DE, Shaffer PL, et al. (2004) Ligand-induced conformational shift in the N-terminal domain of GRP94, an Hsp90 chaperone. The Journal of Biological Chemistry. 279: 46162-71 |
| Shaffer PL, Gewirth DT. (2004) Structural analysis of RXR-VDR interactions on DR3 DNA. The Journal of Steroid Biochemistry and Molecular Biology. 89: 215-9 |
| Shaffer PL, Gewirth DT. (2004) Vitamin D receptor-DNA interactions. Vitamins and Hormones. 68: 257-73 |
| Shaffer PL, Jivan A, Dollins DE, et al. (2004) Structural basis of androgen receptor binding to selective androgen response elements. Proceedings of the National Academy of Sciences of the United States of America. 101: 4758-63 |
| Shaffer PL, Gewirth DT. (2002) Structural basis of VDR-DNA interactions on direct repeat response elements. The Embo Journal. 21: 2242-52 |