Tsz K. Fung, Ph.D.

Affiliations: 
2006 Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong 
Area:
Cell Biology
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"Tsz Fung"
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Randy Y. C. Poon grad student 2006 HKUST
 (The functions and proteolysis of cyclin A and cyclin F during mitosis.)
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Publications

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Luo H, Zhu G, Xu J, et al. (2019) HOTTIP lncRNA Promotes Hematopoietic Stem Cell Self-Renewal Leading to AML-like Disease in Mice. Cancer Cell
Luo H, Zhu G, Fung TK, et al. (2019) Hottip Lncrna Reinforces CTCF Defined Chromatin Boundaries and Drives Wnt Target Gene Expression in AML Leukemogenesis Blood. 134: 277-277
Fung TK, Zeisig B, Zarowiecki M, et al. (2019) Reconstruction of Human AML Reveals Stem Cell Origin and Therapeutic Targets for Treatment Resistant CD34-/Lo MLL-Rearranged Leukemia Blood. 134: 3203-3203
Siriboonpiputtana T, Zeisig BB, Zarowiecki M, et al. (2017) Transcriptional memory of cells of origin overrides β-catenin requirement of MLL cancer stem cells. The Embo Journal
Cheung N, Fung TK, Zeisig BB, et al. (2016) Targeting Aberrant Epigenetic Networks Mediated by PRMT1 and KDM4C in Acute Myeloid Leukemia. Cancer Cell. 29: 32-48
Esposito MT, Zhao L, Fung TK, et al. (2015) Synthetic lethal targeting of oncogenic transcription factors in acute leukemia by PARP inhibitors. Nature Medicine
Man CH, Fung TK, Wan H, et al. (2015) Suppression of SOX7 by DNA methylation and its tumor suppressor function in acute myeloid leukemia. Blood. 125: 3928-36
Fung TK, So CWE. (2013) Overcoming treatment resistance in acute promyelocytic leukemia and beyond Oncotarget. 4: 1128-1129
Fung TK, Gandillet A, So CW. (2012) Selective treatment of mixed-lineage leukemia leukemic stem cells through targeting glycogen synthase kinase 3 and the canonical Wnt/β-catenin pathway. Current Opinion in Hematology. 19: 280-6
Man CH, Fung TK, Ho C, et al. (2012) Sorafenib treatment of FLT3-ITD(+) acute myeloid leukemia: favorable initial outcome and mechanisms of subsequent nonresponsiveness associated with the emergence of a D835 mutation. Blood. 119: 5133-43
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