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Harriet C. Isom

Affiliations: 
Microbiology and Immunology Pennsylvania State University, State College, PA, United States 
Area:
Microbiology Biology, Physiology Biology
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Ayman M. Abdelhamed grad student 2002 Penn State
John P. Bilello grad student 2002 Penn State
Heather A. Iocca grad student 2003 Penn State
Stephanie A. Stoehr grad student 2004 Penn State
Richard A. Heipertz grad student 2009 Penn State
Andrea S. Blevins Primeau grad student 2011 Penn State

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Publications

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Moon MS, McDevitt EI, Zhu J, et al. (2012) Elevated hepatic iron activates NF-E2-related factor 2-regulated pathway in a dietary iron overload mouse model. Toxicological Sciences : An Official Journal of the Society of Toxicology. 129: 74-85
Moon MS, Kang BH, Krzeminski J, et al. (2011) 3,5,5-trimethyl-hexanoyl-ferrocene diet protects mice from moderate transient acetaminophen-induced hepatotoxicity. Toxicological Sciences : An Official Journal of the Society of Toxicology. 124: 348-58
Moon MS, Richie JP, Isom HC. (2010) Iron potentiates acetaminophen-induced oxidative stress and mitochondrial dysfunction in cultured mouse hepatocytes. Toxicological Sciences : An Official Journal of the Society of Toxicology. 118: 119-27
McDevitt E, Moon MS, Kocher S, et al. (2010) Abstract 1886: Selenium prevents specific iron-mediated hepatic cellular changes associated with antioxidant defense and proliferation Cancer Research. 70: 1886-1886
Isom HC, McDevitt EI, Moon MS. (2009) Elevated hepatic iron: a confounding factor in chronic hepatitis C. Biochimica Et Biophysica Acta. 1790: 650-62
Heipertz RA, Starkey JL, Miller TG, et al. (2009) trans-Complementation of HBV rtM204I mutant replication by HBV wild-type polymerase. Virology. 388: 57-67
Starkey JL, Chiari EF, Isom HC. (2009) Hepatitis B virus (HBV)-specific short hairpin RNA is capable of reducing the formation of HBV covalently closed circular (CCC) DNA but has no effect on established CCC DNA in vitro. The Journal of General Virology. 90: 115-26
Shan W, Palkar PS, Murray IA, et al. (2008) Ligand activation of peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) attenuates carbon tetrachloride hepatotoxicity by downregulating proinflammatory gene expression. Toxicological Sciences : An Official Journal of the Society of Toxicology. 105: 418-28
Heipertz RA, Miller TG, Kelley CM, et al. (2007) In vitro study of the effects of precore and lamivudine-resistant mutations on hepatitis B virus replication. Journal of Virology. 81: 3068-76
Isom HC, Heipertz RA, Miller TG, et al. (2007) The lamivudine resistant mutation rtM204I and its effect on HBV replication in vitro The Faseb Journal. 21
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