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Victor R. Guarino, Ph.D.

Affiliations: 
2004 University of Kansas, Lawrence, KS, United States 
Area:
Pharmaceutical Chemistry
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Valentino J. Stella grad student 2004 University of Kansas
 (Sulfenamide prodrugs: A novel prodrug approach for amides, imides and other NH-acidic compounds.)

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Guarino VR, Olson RE, Everlof JG, et al. (2019) An amide-based sulfenamide prodrug of gamma secretase inhibitor BMS-708163 delivers parent drug from an oral conventional solid dosage form in male beagle dog. Bioorganic & Medicinal Chemistry Letters. 126856
Nti-Addae KW, Guarino VR, Dalwadi G, et al. (2012) Determination of the permeability characteristics of two sulfenamide prodrugs of linezolid across Caco-2 cells. Journal of Pharmaceutical Sciences. 101: 3134-41
Guarino VR, Nti-Addae K, Stella VJ. (2011) Reprint of "MDCK cell permeability characteristics of a sulfenamide produg: strategic implications in considering sulfenamide prodrugs for oral delivery of NH acids" [Bioorg. Med. Chem. Lett. 21 (2011) 172-175]. Bioorganic & Medicinal Chemistry Letters. 21: 2780-3
Guarino VR, Nti-Addae K, Stella VJ. (2011) MDCK cell permeability characteristics of a sulfenamide prodrug: strategic implications in considering sulfenamide prodrugs for oral delivery of NH-acids. Bioorganic & Medicinal Chemistry Letters. 21: 172-5
Hemenway JN, Nti-Addae K, Guarino VR, et al. (2007) Preparation, characterization and in vivo conversion of new water-soluble sulfenamide prodrugs of carbamazepine. Bioorganic & Medicinal Chemistry Letters. 17: 6629-32
Guarino VR, Karunaratne V, Stella VJ. (2007) Sulfenamides as prodrugs of NH-acidic compounds: a new prodrug option for the amide bond. Bioorganic & Medicinal Chemistry Letters. 17: 4910-3
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