Gihani T. Wijewickrama, Ph.D.

2008 University of Illinois at Chicago, Chicago, IL, United States 
"Gihani Wijewickrama"
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Wondwa Cho grad student 2008 University of Illinois, Chicago
 (Membrane binding and activation mechanisms of phospholipase A2 and 5-Lipoxygenase.)
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Schiefer IT, Tapadar S, Litosh V, et al. (2013) Design, synthesis, and optimization of novel epoxide incorporating peptidomimetics as selective calpain inhibitors. Journal of Medicinal Chemistry. 56: 6054-68
Dietz BM, Hagos GK, Eskra JN, et al. (2013) Differential regulation of detoxification enzymes in hepatic and mammary tissue by hops (Humulus lupulus) in vitro and in vivo. Molecular Nutrition & Food Research. 57: 1055-66
Dunlap T, Piyankarage SC, Wijewickrama GT, et al. (2012) Quinone-induced activation of Keap1/Nrf2 signaling by aspirin prodrugs masquerading as nitric oxide. Chemical Research in Toxicology. 25: 2725-36
Kastrati I, Edirisinghe PD, Wijewickrama GT, et al. (2010) Estrogen-induced apoptosis of breast epithelial cells is blocked by NO/cGMP and mediated by extranuclear estrogen receptors. Endocrinology. 151: 5602-16
Sinha V, Wijewickrama GT, Chandrasena RE, et al. (2010) Proteomic and mass spectroscopic quantitation of protein S-nitrosation differentiates NO-donors. Acs Chemical Biology. 5: 667-80
Kim HY, Sohn J, Wijewickrama GT, et al. (2010) Click synthesis of estradiol-cyclodextrin conjugates as cell compartment selective estrogens. Bioorganic & Medicinal Chemistry. 18: 809-21
Peng KW, Wang H, Qin Z, et al. (2009) Selective estrogen receptor modulator delivery of quinone warheads to DNA triggering apoptosis in breast cancer cells. Acs Chemical Biology. 4: 1039-49
Yu B, Qin Z, Wijewickrama GT, et al. (2009) Comparative methods for analysis of protein covalent modification by electrophilic quinoids formed from xenobiotics. Bioconjugate Chemistry. 20: 728-41
Wang Z, Wijewickrama GT, Peng KW, et al. (2009) Estrogen Receptor {alpha} Enhances the Rate of Oxidative DNA Damage by Targeting an Equine Estrogen Catechol Metabolite to the Nucleus. The Journal of Biological Chemistry. 284: 8633-42
Tian W, Wijewickrama GT, Kim JH, et al. (2008) Mechanism of regulation of group IVA phospholipase A2 activity by Ser727 phosphorylation. The Journal of Biological Chemistry. 283: 3960-71
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