Stefano V. Gulla, Ph.D.

Affiliations: 
2009 Chemistry Northeastern University, Boston, MA, United States 
Area:
Biochemistry, Physical Chemistry, Medical Biophysics
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"Stefano Gulla"
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Parents

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David E. Budil grad student 2009 Northeastern University
 (EPR study of ligand -receptor interactions: Measuring ligand induced changes in dynamics and structure of the estrogen receptor ligand binding domain.)
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Publications

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Foight GW, Ryan JA, Gullá SV, et al. (2014) Designed BH3 peptides with high affinity and specificity for targeting Mcl-1 in cells. Acs Chemical Biology. 9: 1962-8
London N, Gullá S, Keating AE, et al. (2012) In silico and in vitro elucidation of BH3 binding specificity toward Bcl-2. Biochemistry. 51: 5841-50
Hendricks JA, Gullà SV, Budil DE, et al. (2012) Synthesis of a spin-labeled anti-estrogen as a dynamic motion probe for the estrogen receptor ligand binding domain. Bioorganic & Medicinal Chemistry Letters. 22: 1743-6
Han S, Ma Z, Hopson R, et al. (2012) Postsynthetic modification of a coordination compound with a paddlewheel motif via click reaction: DOSY and ESR studies Inorganic Chemistry Communications. 15: 78-83
Dutta S, Gullá S, Chen TS, et al. (2010) Determinants of BH3 Binding Specificity for Mcl-1 versus Bcl-xL Journal of Molecular Biology. 398: 747-762
Fire E, Gullá SV, Grant RA, et al. (2010) Mcl-1-Bim complexes accommodate surprising point mutations via minor structural changes Protein Science. 19: 507-519
Tiburu EK, Gulla SV, Tiburu M, et al. (2009) Dynamic conformational responses of a human cannabinoid receptor-1 helix domain to its membrane environment. Biochemistry. 48: 4895-904
Gullà SV, Sharma G, Borbat P, et al. (2009) Molecular-scale force measurement in a coiled-coil peptide dimer by electron spin resonance. Journal of the American Chemical Society. 131: 5374-5
Gulla SV. (2009) Dynamic and Strucutral Effects of Ligand and Coregulator Binding on Estrogen Receptor Ligand Binding Domain Measured by Electron Paramagnetic Resonance Biophysical Journal. 96
Gulla SV, Budil DE. (2007) Ligand Induced Solution Structure and Dynamics of the Helix‐12 region of Estrogen Receptor Alpha The Faseb Journal. 21
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