Jason M. Ridlon, Ph.D.

Affiliations: 
2008 Virginia Commonwealth University, Richmond, VA, United States 
Area:
Microbiology Biology, Molecular Biology, Biochemistry
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Phillip B. Hylemon grad student 2008 VCU
 (Enzymology and molecular biology of bile acid 7alpha- and 7beta-dehydroxylation by the intestinal bacteria Clostridium scindens and Clostridium hylemonae.)
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Publications

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Ly LK, Rowles JL, Paul HM, et al. (2019) Bacterial steroid-17,20-desmolase is a taxonomically rare enzymatic pathway that converts prednisone to 1,4-androstanediene-3,11,17-trione, a metabolite that causes proliferation of prostate cancer cells. The Journal of Steroid Biochemistry and Molecular Biology. 105567
Doden HL, Pollet RM, Mythen SM, et al. (2019) Structural and biochemical characterization of 20β-hydroxysteroid dehydrogenase from strain L2-32. The Journal of Biological Chemistry
Ridlon JM, Devendran S, Alves JM, et al. (2019) The ' lifestyle' of bile acid 7α-dehydroxylating bacteria: comparative genomics, metatranscriptomic, and bile acid metabolomics analysis of a defined microbial community in gnotobiotic mice. Gut Microbes. 1-24
Devendran S, Shrestha R, Alves JMP, et al. (2019) ATCC 35704: integration of nutritional requirements, the complete genome sequence, and global transcriptional responses to bile acids. Applied and Environmental Microbiology
Alexander C, Cross TL, Devendran S, et al. (2018) Effects of prebiotic inulin-type fructans on blood metabolite and hormone concentrations and faecal microbiota and metabolites in overweight dogs. The British Journal of Nutrition. 1-10
Hylemon PB, Harris SC, Ridlon JM. (2018) Metabolism of hydrogen gases and bile acids in the gut microbiome. Febs Letters
Harris SC, Devendran S, Méndez-García C, et al. (2018) Bile acid oxidation by Eggerthella lenta strains C592 and DSM 2243. Gut Microbes. 1-58
Devendran S, Mythen SM, Ridlon JM. (2018) The desA and desB genes from Clostridium scindens ATCC 35704 encode steroid-17,20-desmolase. Journal of Lipid Research
Doden H, Sallam LA, Devendran S, et al. (2018) Metabolism of oxo-bile acids and characterization of recombinant 12α-hydroxysteroid dehydrogenases from bile acid 7α-dehydroxylating human gut bacteriaATCC 35704,DSM 15053 andDSM 13275. Applied and Environmental Microbiology
Mythen SM, Devendran S, Méndez-García C, et al. (2018) Targeted synthesis and characterization of a gene-cluster encoding NAD(P)H-dependent 3α-, 3β-, and 12α-hydroxysteroid dehydrogenases from Eggerthella CAG:298, a gut metagenomic sequence. Applied and Environmental Microbiology
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