Samer Abdul-Hay, Ph.D.

Affiliations: 
2009 University of Illinois at Chicago, Chicago, IL, United States 
Area:
Pharmacology, Neuroscience Biology, Pharmacy
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Gregory Thatcher grad student 2009 University of Illinois, Chicago
 (Exploring the use of hybrid organic nitrates for the treatment of Alzheimer's disease.)
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Publications

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Li H, Zhu H, Wallack M, et al. (2015) Age and Its Association with Low Insulin and High Amyloid-β Peptides in Blood. Journal of Alzheimer's Disease : Jad
Abdul-Hay SO, Bannister TD, Wang H, et al. (2015) Selective targeting of extracellular insulin-degrading enzyme by quasi-irreversible thiol-modifying inhibitors. Acs Chemical Biology
Medway CW, Abdul-Hay S, Mims T, et al. (2014) ApoE variant p.V236E is associated with markedly reduced risk of Alzheimer's disease. Molecular Neurodegeneration. 9: 11
Kurklinsky S, Abdul-Hay SO, McGuire MP, et al. (2014) The blood glucose-lowering effect of racecadotril is not attributable to inhibition of insulin-degrading enzyme. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Mã©Tabolisme. 46: 73-4
Lincoln S, Allen M, Cox CL, et al. (2013) LRRTM3 interacts with APP and BACE1 and has variants associating with late-onset Alzheimer's disease (LOAD). Plos One. 8: e64164
Abdul-Hay SO, Lane AL, Caulfield TR, et al. (2013) Optimization of peptide hydroxamate inhibitors of insulin-degrading enzyme reveals marked substrate-selectivity. Journal of Medicinal Chemistry. 56: 2246-55
Dunlap T, Piyankarage SC, Wijewickrama GT, et al. (2012) Quinone-induced activation of Keap1/Nrf2 signaling by aspirin prodrugs masquerading as nitric oxide. Chemical Research in Toxicology. 25: 2725-36
Abdul-Hay SO, Sahara T, McBride M, et al. (2012) Identification of BACE2 as an avid ß-amyloid-degrading protease. Molecular Neurodegeneration. 7: 46
Liu Z, Zhu H, Fang GG, et al. (2012) Characterization of insulin degrading enzyme and other amyloid-β degrading proteases in human serum: a role in Alzheimer's disease? Journal of Alzheimer's Disease : Jad. 29: 329-40
Abdul-Hay S, Schiefer IT, Chandrasena RE, et al. (2011) NO-SSRIs: Nitric Oxide Chimera Drugs Incorporating a Selective Serotonin Reuptake Inhibitor. Acs Medicinal Chemistry Letters. 2: 656-661
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